1383993-10-9

Basic information

• Product Name: N-[2-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-3-yl]benzenesulfonamide
• Synonyms: N-[2-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-3-yl]benzenesulfonamide
• CAS NO: 1383993-10-9
• Molecular Weight: 374.269
• Mol File: 1383993-10-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-[2-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-3-yl]benzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-[2-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-3-yl]benzenesulfonamide(1383993-10-9)
• EPA Substance Registry System: N-[2-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-3-yl]benzenesulfonamide(1383993-10-9)

Safety Data

• Hazardous Substances Data: 1383993-10-9(Hazardous Substances Data)

Upstream product

• 98-09-9 benzenesulfonyl chloride 
• 588729-99-1 3-amino-5-bromo-2-chloropyridine 
• 914358-73-9 5-bromo-2-methylpyridin-3-ylamine 
• 1083326-17-3 N-(5-bromo-2-chloropyridin-3-yl)benzenesulfonamide 
• 73183-34-3 bis(pinacol)diborane 
• 1083326-24-2 N-(5-bromo-2-methylpyridin-3-yl)benzenesulfonamide 

Relevant articles and documents

Discovery of a Novel Series of 7-Azaindole Scaffold Derivatives as PI3K Inhibitors with Potent Activity

The phosphoinositide 3-kinase (PI3K) inhibitors potently inhibit the signaling pathway of PI3K/AKT/mTOR, which provides a promising new approach for the molecularly targeted cancer therapy. In this work, a novel series of 7-azaindole scaffold derivatives was discovered by the fragment-based growing strategy. The structure-activity relationship profiles identified that the 7-azaindole scaffold derivatives exhibit potent activity against PI3K at molecular and cellular levels as well as cell proliferation in a panel of human tumor cells.