13841-66-2

Usage

Uses

Used in Food Industry:
N-BUTYL ISONICOTINATE is used as a flavoring agent for enhancing the taste and aroma of food products.
Used in Cosmetic Industry:
N-BUTYL ISONICOTINATE is used as a fragrance ingredient in perfumes, colognes, and other personal care products to provide a pleasant scent.
Used in Pharmaceutical Industry:
N-BUTYL ISONICOTINATE is used in the production of pharmaceuticals due to its potential therapeutic properties.
Used in Veterinary Medicine:
N-BUTYL ISONICOTINATE is used in the production of veterinary medicines for its potential therapeutic benefits.
Used in Industrial Applications:
N-BUTYL ISONICOTINATE serves as a solvent and can be found in various industrial applications.

InChI:InChI=1/C10H13NO2/c1-2-3-8-13-10(12)9-4-6-11-7-5-9/h4-7H,2-3,8H2,1H3

Upstream product

• 55-22-1 pyridine-4-carboxylic acid 
• 71-36-3 butan-1-ol 
• 15854-87-2 4-iodopyridine 
• 201230-82-2 carbon monoxide 
• 39178-35-3 isonicotinoyl chloride hydrochloride 
• 1903-64-6 N,N-dimethylisonicotineamide 
• 6265-74-3 isonicotinic acid N-(β-hydroxyethyl)amide 

Downstream Products

• 54-85-3 isoniazid 
• 923571-15-7 5,6-dimethoxy-2-(pyridine-4-carbonyl)indan-1-one 

Relevant academic research and scientific papers

Synthesis and structures of 1,2,4-triazoles derivatives

Abstract A series of novel 1,2,4-triazole derivatives were synthesized, and their structures were characterized by IR, UV-Vis, FL, NMR, ESI-MS, and elemental analysis. In the meanwhile, the single crystal structures of 3,4-diethyl-5-(4-pyridyl)-1,2,4-triazole and 3,4-dimethyl-5-(o-hydroxyphenyl)-1,2,4-triazole were determined by X-ray diffraction.

Dinuclear manganese alkoxide complexes as catalysts for C-N bond cleavage of simple tertiary: N, N -dialkylamides to give esters

Amide bonds are stable due to the resonance between the nitrogen lone pair and the carbonyl moiety, and therefore the chemical transformation of amides, especially tertiary amides, involving C-N bond fission is considered one of the most difficult organic reactions, unavoidably requiring harsh reaction conditions and strong acids or bases. We report the catalytic C-N bond cleavage of simple tertiary N,N-dialkylamides to give corresponding esters using a catalyst system (2 mol% based on Mn atoms) of a tetranuclear manganese alkoxide, [Mn(acac)(OEt)(EtOH)]4 (1c), combined with four equivalents of 4,7-bis(dimethylamino)-1,10-phenanthroline (L1: Me2N-Phen). Regarding the reaction mechanism, we isolated a dinuclear manganese complex, [Mn(acac)(OEt)(Phen)]2 (6c), which was revealed as the catalytically active species for the esterification of tertiary amides.

Manganese(II)-Catalyzed Esterification of N-β-Hydroxyethylamides

A catalyst system of manganese with 2,2-bipyridine for amide alcoholysis of N-β-hydroxyethylamides is described. This protocol enabled selective cleavage of the amide bond through a mechanism involving sequential N,O-acyl rearrangement and transesterification.

Polyurea-encapsulated palladium(II) acetate: A robust and recyclable catalyst for use in conventional and supercritical media

Palladium(II) acetate microencapsulated in polyurea (MC-[Pd]) is an economical and versatile heterogeneous catalyst for a range of phosphine-free cross-coupling reactions in both conventional solvents and supercritical carbon dioxide (scCO2); the catalyst can be recovered by a simple filtration and recycled up to four times.