138415-95-9Relevant academic research and scientific papers
A Novel Stereospecific Rearrangement of 3-Substituted B-Homo 5-Azasteroids to Their A-Nor Analogues. Preparation, Stereochemistry, and Conformational Studies
Back, Thomas G.,Chau, Joseph H.-L.,Codding, Penelope W.,Gladstone, Patricia L.,Jones, David H.,et al.
, p. 4110 - 4121 (2007/10/02)
The novel 3α- and 3β-hydroxy-B-homo-5-azasteroid lactams 4 and 5 were prepared from testosterone.When the hydroxyl group in these compounds is converted into a leaving group, rearrangement to the corresponding A-nor azasteroids occurs under a variety of c
A NOVEL STEREOSPECIFIC REARRANGEMENT OF 3-SUBSTITUTED B-HOMO-5-AZASTEROID LACTAMS TO A-NOR ANALOGUES
Back, Thomas G.,Chau, Joseph H.-L.,Morzycki, Jacek W.
, p. 6517 - 6520 (2007/10/02)
B-Homo-5-azasteroid lactams containing nucleofugal substituents in the 3-position (1 and 2) undergo rearrangement via stereospecific ring contractions to afford A-nor analogues 3 and 4.
