1384878-23-2

Basic information

• Product Name: 2-chloro-6-(trifluoromethoxy)-5-(trimethylsilyl)nicotinic acid
• Synonyms: 2-chloro-6-(trifluoromethoxy)-5-(trimethylsilyl)nicotinic acid
• CAS NO: 1384878-23-2
• Molecular Weight: 313.736
• Mol File: 1384878-23-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-chloro-6-(trifluoromethoxy)-5-(trimethylsilyl)nicotinic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-chloro-6-(trifluoromethoxy)-5-(trimethylsilyl)nicotinic acid(1384878-23-2)
• EPA Substance Registry System: 2-chloro-6-(trifluoromethoxy)-5-(trimethylsilyl)nicotinic acid(1384878-23-2)

Safety Data

• Hazardous Substances Data: 1384878-23-2(Hazardous Substances Data)

Upstream product

• 1221171-70-5 2-chloro-6-(trifluoromethoxy)pyridine 

Downstream Products

• 1221172-04-8 2-chloro-6-(trifluoromethoxy)nicotinic acid 
• 940895-85-2 6-(trifluoromethoxy)nicotinic acid 
• 1384878-12-9 3-hydroxy-4-(4-isopropylbenzoyl)-1-(6-methylpyridazin-3-yl)-5(R)-(6-(trifluoromethoxy)pyridin-3-yl)-1H-pyrrol-2(5H)-one 
• 1384878-11-8 3-hydroxy-4-(4-isopropylbenzoyl)-1-(6-methylpyridazin-3-yl)-5(S)-(6-(trifluoromethoxy)pyridin-3-yl)-1H-pyrrol-2(5H)-one 
• 1384878-02-7 3-hydroxy-4-(4-isopropylbenzoyl)-1-(6-methylpyridazin-3-yl)-5-(6-(trifluoromethoxy)pyridin-3-yl)-1H-pyrrol-2(5H)-one 

Relevant articles and documents

2-AMINO-N-PHENYL-NICOTINAMIDES AS NAV1.8 INHIBITORS

Novel compounds of the structural formula (I), and the pharmaceutically acceptable salts thereof, are inhibitors of Nav1.8 channel activity and may be useful in the treatment, prevention, management, amelioration, control and suppression of diseases mediated by Nav1.8 channel activity. The compounds of the present invention may be useful in the treatment, prevention or management of pain disorders, cough disorders, acute itch disorders, and chronic itch disorders.