1384878-11-8

Basic information

• Product Name: 3-hydroxy-4-(4-isopropylbenzoyl)-1-(6-methylpyridazin-3-yl)-5(S)-(6-(trifluoromethoxy)pyridin-3-yl)-1H-pyrrol-2(5H)-one
• Synonyms: 3-hydroxy-4-(4-isopropylbenzoyl)-1-(6-methylpyridazin-3-yl)-5(S)-(6-(trifluoromethoxy)pyridin-3-yl)-1H-pyrrol-2(5H)-one
• CAS NO: 1384878-11-8
• Molecular Weight: 498.461
• Mol File: 1384878-11-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-hydroxy-4-(4-isopropylbenzoyl)-1-(6-methylpyridazin-3-yl)-5(S)-(6-(trifluoromethoxy)pyridin-3-yl)-1H-pyrrol-2(5H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-hydroxy-4-(4-isopropylbenzoyl)-1-(6-methylpyridazin-3-yl)-5(S)-(6-(trifluoromethoxy)pyridin-3-yl)-1H-pyrrol-2(5H)-one(1384878-11-8)
• EPA Substance Registry System: 3-hydroxy-4-(4-isopropylbenzoyl)-1-(6-methylpyridazin-3-yl)-5(S)-(6-(trifluoromethoxy)pyridin-3-yl)-1H-pyrrol-2(5H)-one(1384878-11-8)

Safety Data

• Hazardous Substances Data: 1384878-11-8(Hazardous Substances Data)

Upstream product

• 1361849-85-5 6-(trifluoromethoxy)nicotinaldehyde 
• 852814-99-4 ethyl 4-[4-(1-methylethyl)phenyl]-2,4-dioxobutanoate 
• 16879-02-0 6-chloro-2-hydroxypyridine 
• 1221172-02-6 2-chloro-6-(trifluoromethoxy)-5-(trimethylsilyl)pyridine 
• 1221172-04-8 2-chloro-6-(trifluoromethoxy)nicotinic acid 
• 1384878-23-2 2-chloro-6-(trifluoromethoxy)-5-(trimethylsilyl)nicotinic acid 
• 940895-85-2 6-(trifluoromethoxy)nicotinic acid 
• 1221171-70-5 2-chloro-6-(trifluoromethoxy)pyridine 
• 1221171-69-2 2-chloro-6-(trichloromethoxy)pyridine 
• 645-13-6 4-isopropylacetophenone 
• 1384878-24-3 N-methoxy-N-methyl-6-(trifluoromethoxy)nicotinamide 
• 1384878-02-7 3-hydroxy-4-(4-isopropylbenzoyl)-1-(6-methylpyridazin-3-yl)-5-(6-(trifluoromethoxy)pyridin-3-yl)-1H-pyrrol-2(5H)-one 

Relevant articles and documents

1-(6-MEMBERED AZO-HETEROCYCLIC)-2,5-DIHYDRO-1H-PYRROL-2-ONE DERIVATIVES AS ANTI-HEPATITIS C VIRUS, THE PHARMACEUTICAL COMPOSITION THEREOF AND THEIR THERAPEUTIC USE

The present invention concerns 1-(6-memberedazo-heterocyclic)-2,5-dihydro–1H–pyrrol–2-one compoundsof the following formula (I) or a salt, solvate, tautomer, isotope, enantiomer, diastereoisomer or racemic mixture thereof: the pharmaceutical composition thereof and their therapeutic use as inhibitors of Hepatitis C virus.