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(3S)-TETRAHYDROFURANYLSUCCINIMIDYL-CARBONATE, also known as Carbonic Acid 2,5-Dioxopyrrolidin-1-yl (S)-Tetrahydrofuran-3-yl Ester, is an off-white solid compound with the CAS number 138499-08-8. It is a versatile compound used in various organic synthesis processes due to its unique chemical properties.

138499-08-8

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  • Carbonicacid, 2,5-dioxo-1-pyrrolidinyl (3S)-tetrahydro-3-furanyl ester

    Cas No: 138499-08-8

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138499-08-8 Usage

Uses

Used in Organic Synthesis:
(3S)-TETRAHYDROFURANYLSUCCINIMIDYL-CARBONATE is used as a synthetic building block for the creation of various organic compounds. Its unique structure allows it to be a valuable intermediate in the synthesis of complex molecules, particularly in the pharmaceutical and chemical industries.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, (3S)-TETRAHYDROFURANYLSUCCINIMIDYL-CARBONATE is used as a key component in the development of new drugs. Its ability to form complex molecular structures makes it an essential tool in the design and synthesis of novel therapeutic agents.
Used in Chemical Industry:
(3S)-TETRAHYDROFURANYLSUCCINIMIDYL-CARBONATE is also utilized in the chemical industry for the production of specialty chemicals and materials. Its versatility in organic synthesis allows for the creation of a wide range of products, from advanced materials to fine chemicals.

Check Digit Verification of cas no

The CAS Registry Mumber 138499-08-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,8,4,9 and 9 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 138499-08:
(8*1)+(7*3)+(6*8)+(5*4)+(4*9)+(3*9)+(2*0)+(1*8)=168
168 % 10 = 8
So 138499-08-8 is a valid CAS Registry Number.
InChI:InChI=1/C9H11NO6/c11-7-1-2-8(12)10(7)16-9(13)15-6-3-4-14-5-6/h6H,1-5H2/t6-/m0/s1

138499-08-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name (2,5-dioxopyrrolidin-1-yl) [(3S)-oxolan-3-yl] carbonate

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:138499-08-8 SDS

138499-08-8Relevant articles and documents

COMPOSITION FOR TREATMENT AND/OR PREVENTION OF PERIPHERAL NERVE DISORDER

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Paragraph 0153, (2019/10/29)

The present invention provides a means for treating and/or preventing peripheral nerve disorder by facilitating regeneration of peripheral nerves. Specifically, the present invention provides a composition for treating and/or preventing peripheral nerve d

OXAZEPINE DERIVATIVES HAVING TNAP INHIBITORY ACTIVITY

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Page/Page column 88-89, (2018/07/29)

The present invention relates to a compound or a pharmacologically acceptable salt thereof having excellent tissue non-specific alkaline phosphatase inhibitory activity. The present invention provides a compound represented by the formula (I) or a pharmacologically acceptable salt thereof.

Lissencephaly therapeutic agent

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Page/Page column 31; 42, (2016/07/27)

An object of the present invention is to provide a medicament and method for treating lissencephaly patients. The present invention provides a lissencephaly therapeutic or preventive agent comprising a compound represented by the general formula (I): wher

PROCESS FOR SYNTHESIS OF SYN AZIDO EPOXIDE AND ITS USE AS INTERMEDIATE FOR THE SYNTHESIS OF AMPRENAVIR and SAQUINAVIR

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Paragraph 0083, (2015/02/18)

Disclosed herein is a novel route of synthesis of syn azide epoxide of formula 5, which is used as a common intermediate for asymmetric synthesis of HIV protease inhibitors such as Amprenavir, Fosamprenavir, Saquinavir and formal synthesis of Darunavir an

A PROCESS FOR SYNTHESIS OF SYN AZIDO EPOXIDE AND ITS USE AS INTERMEDIATE THE SYNTHESIS OF AMPRENAVIR and SAQUINAVIR

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Page/Page column 23-24, (2013/07/25)

Disclosed herein is a novel route of synthesis of syn azide epoxide of formu 5, which is used as a common intermdeiate for asymmetric synthesis of HIV protease inhibitors such as Amprenavir, Fosamprenavir, Saquinavir and formal synthesis of Darunavir and

PROCESS FOR PREPARATION OF SUBSTANTIALLY PURE FOSAMPRENAVIR CALCIUM AND ITS INTERMEDIATES

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Paragraph 0050, (2013/07/19)

The present invention relates to fosamprenavir calcium (Ia) substantially free of isomer impurity, (3R) tetrahydro -3 -furanyl(1S,2R)-3-[[(4-aminophenyl)sulfonyl](isobutyl)amino]-1-benzyl-2-(phosphonooxy)propyl carbamate (Ib), and its process for preparat

LISSENCEPHALY THERAPEUTIC AGENT

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Page/Page column, (2013/10/22)

An object of the present invention is to provide a medicament and method for treating lissencephaly patients. The present invention provides a lissencephaly therapeutic or preventive agent comprising a compound represented by the general formula (I): wher

Enantioselective synthesis of HIV protease inhibitor amprenavir via Co-catalyzed HKR of 2-(1-azido-2-phenylethyl)oxirane

Gadakh, Sunita K.,Santhosh Reddy,Sudalai, Arumugam

experimental part, p. 898 - 903 (2012/09/22)

A short and efficient enantioselective synthesis of the HIV protease inhibitor amprenavir 1 (99% ee) as well as a formal synthesis of saquinavir 3 have been achieved in high enantiomeric purity starting from commercially available materials. Our strategy mainly comprises a Co-catalyzed two-stereocentred hydrolytic kinetic resolution (HKR) of racemic 2-(1-azido-2-phenylethyl)oxirane as the chirality inducing step. Also presented is a concise synthesis of (S)-3-hydroxytetrahydrofuran 4, the key structural feature, in high enantiomeric purity (98% ee).

PROCESS FOR PREPARATION OF SUBSTANTIALLY PURE FOSAMPRENAVIR CALCIUM AND ITS INTERMEDIATES

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Page/Page column 14, (2012/03/27)

The present invention relates to fosamprenavir calcium (la) substantially free of isomer impurity, (3R) tetrahydro-3-furanyl(1S,2R)-3-[[(4-aminophenyl) sulfonyl] (isobutyl) amino]- 1-benzyl-2-(phosphonooxy)propyl carbamate (lb), and its process for prepar

METHOD AND COMPOSITIONS FOR TREATING HIV INFECTIONS

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Page/Page column 34, (2008/12/08)

Described herein are compounds and compositions that are useful in the treatment of HIV, AIDS, and AIDS-related diseases. In addition, compounds are described herein that are capable of inhibiting the dimerization of HIV proteases.

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