138499-08-8

Basic information

• Product Name: (3S)-TETRAHYDROFURANYLSUCCINIMIDYL-CARBONATE
• Synonyms: (3S)-TETRAHYDROFURANYLSUCCINIMIDYL-CARBONATE;Carbonic Acid 2,5-Dioxopyrrolidin-1-yl (S)-Tetrahydrofuran-3-yl Ester;1-[[[[(3S)-Tetrahydro-3-furanyl]oxy]carbonyl]oxy]-2,5-pyrrolidinedione;3(S)-Hydroxy Tetrahydrofuran, N-HydroxysuccinaMidylcarbonate;(3S)-TetrahydrofuranylsuccinMidyl-carbonate;(S)-2,5-dioxopyrrolidin-1-yl (tetrahydrofuran-3-yl) carbonate
• CAS NO: 138499-08-8
• Molecular Formula: C₉H₁₁NO₆
• Molecular Weight: 229.05
• Product Categories: Miscellaneous Reagents
• Mol File: 138499-08-8.mol
• Article Data: 17

Chemical Properties

• Melting Point: 114-117°C
• Boiling Point: 338.736 °C at 760 mmHg
• Flash Point: 158.662 °C
• Appearance: Off-white solid
• Density: 1.457 g/cm³
• Vapor Pressure: 9.63E-05mmHg at 25°C
• Refractive Index: 1.536
• Storage Temp.: Hygroscopic, -20?C Freezer, Under Inert Atmosphere
• Solubility: Chloroform, Dichloromethane, Ethyl Acetate, Ether, Methanol
• CAS DataBase Reference: (3S)-TETRAHYDROFURANYLSUCCINIMIDYL-CARBONATE(CAS DataBase Reference)
• NIST Chemistry Reference: (3S)-TETRAHYDROFURANYLSUCCINIMIDYL-CARBONATE(138499-08-8)
• EPA Substance Registry System: (3S)-TETRAHYDROFURANYLSUCCINIMIDYL-CARBONATE(138499-08-8)

Safety Data

• Hazardous Substances Data: 138499-08-8(Hazardous Substances Data)

Usage

Chemical Properties

Off-White Solid

Uses

Carbonic Acid 2,5-Dioxopyrrolidin-1-yl (S)-Tetrahydrofuran-3-yl Ester (cas# 138499-08-8) is a compound useful in organic synthesis.

InChI:InChI=1/C9H11NO6/c11-7-1-2-8(12)10(7)16-9(13)15-6-3-4-14-5-6/h6H,1-5H2/t6-/m0/s1

Upstream product

• 75-44-5 phosgene 
• 6066-82-6 1-hydroxy-pyrrolidine-2,5-dione 
• 86087-23-2 (S)-3-hydroxytetyrahydrofurane 
• 74124-79-1 di(succinimido) carbonate 

Downstream Products

• 161814-49-9 {(S)-3-[(4-Amino-benzenesulfonyl)-isobutyl-amino]-1-benzyl-2-hydroxy-propyl}-carbamic acid (S)-(tetrahydro-furan-3-yl) ester 
• 1259010-12-2 (S)-tetrahydrofuran-3-yl 3-(2-(5-chloro-1-tosyl-1H-pyrrolo[2,3-b]pyridin-3-yl)-5-fluoropyrimidin-4-ylamino)azetidine-1-carboxylate 
• 1169870-26-1 C₂₅H₃₅N₃O₅S 
• 1601490-32-7 (S)-tetrahydrofuran-3-yl ((2S,3R)-4-((R)-7-fluoro-4-isopropyl-1,1-dioxido-4,5-dihydrobenzo[1,2-f]thiazepin-2(3H)-yl)-3-hydroxy-1-phenylbutan-2-yl)carbamate 
• 1601490-36-1 (S)-tetrahydrofuran-3-yl ((2S,3R)-4-((S)-7-fluoro-4-isopropyl-1,1-dioxido-4,5-dihydrobenzo[1,2-f]thiazepin-2(3H)-yl)-3-hydroxy-1-phenylbutan-2-yl)carbamate 
• 1601490-34-9 (S)-tetrahydrofuran-3-yl ((2S,3R)-4-((R)-4-(4-fluorophenyl)-1,1-dioxido-4,5-dihydrobenzo[1,2-f]thiazepin-2(3H)-yl)-3-hydroxy-1-phenylbutan-2-yl)carbamate 
• 1601490-33-8 (S)-tetrahydrofuran-3-yl ((2S,3R)-4-((R)-4-(tert-butyl)-7-fluoro-1,1-dioxido-4,5-dihydrobenzo[1,2-f]thiazepin-2(3H)-yl)-3-hydroxy-1-phenylbutan-2-yl)carbamate 
• 1601490-37-2 (S)-tetrahydrofuran-3-yl ((2S,3R)-4-((S)-4-(tert-butyl)-7-fluoro-1,1-dioxido-4,5-dihydrobenzo[1,2-f]thiazepin-2(3H)-yl)-3-hydroxy-1-phenylbutan-2-yl)carbamate 
• 161814-49-9 amprenavir 
• 160231-69-6 4-nitro-N-((2R(syn),3S)-2-hydroxy-4-phenyl-3-((S)-tetrahydrofuran-3-yloxycarbonylamino)-butyl)-N-isobutylbenzenesulfonamide 
• 478697-33-5 C₂₉H₃₇N₃O₆S 
• 1217206-83-1 C₂₉H₃₉N₃O₅S 

Relevant articles and documents

COMPOSITION FOR TREATMENT AND/OR PREVENTION OF PERIPHERAL NERVE DISORDER

The present invention provides a means for treating and/or preventing peripheral nerve disorder by facilitating regeneration of peripheral nerves. Specifically, the present invention provides a composition for treating and/or preventing peripheral nerve d

Lissencephaly therapeutic agent

An object of the present invention is to provide a medicament and method for treating lissencephaly patients. The present invention provides a lissencephaly therapeutic or preventive agent comprising a compound represented by the general formula (I): wher

A PROCESS FOR SYNTHESIS OF SYN AZIDO EPOXIDE AND ITS USE AS INTERMEDIATE THE SYNTHESIS OF AMPRENAVIR and SAQUINAVIR

Disclosed herein is a novel route of synthesis of syn azide epoxide of formu 5, which is used as a common intermdeiate for asymmetric synthesis of HIV protease inhibitors such as Amprenavir, Fosamprenavir, Saquinavir and formal synthesis of Darunavir and