138616-61-2

Upstream product

• 487-51-4 4-carbethoxy-3-methyl-2-cyclohexen-1-one 
• 3433-80-5 1-Bromo-2-bromomethyl-benzene 

Downstream Products

• 138616-62-3 2-(o-Bromobenzyl)-3-methylcyclohex-2-en-1-one 
• 138616-64-5 (1S,2R)-2-(2-Bromo-benzyl)-1-methyl-3-methylene-cyclohexanecarboxylic acid methyl ester 
• 138616-63-4 Methyl 2-(o-bromobenzyl)-3-methyl-1-oxocyclohexane-3-carboxylate 
• 150270-99-8 2-(o-Bromobenzyl)-3,3-dimethylcyclohexan-1-one 
• 138616-67-8 2-(o-Bromobenzyl)-3,3-dimethyl-1-methylenecyclohexane 

Relevant academic research and scientific papers

Palladium-Catalyzed Tandem γ-Arylation/Aromatization of Cyclohex-2-En-1-One Derivatives: A Route to 3,4-Dihydroanthracen-1(2H)-Ones

An intramolecular palladium-catalyzed tandem γ-arylation/aromatization reaction of cyclohex-2-en-1-one derivatives was developed. This work provides a simple and efficient approach for the construction of substituted 3,4-dihydroanthracen-1(2H)-ones in good yields with a broad substrate scope. (Figure presented.).

Regioselective Aryl Radical Cyclization. 1. Stereocontrolled Synthesis of Linearly Condensed Hydroaromatic Carbocyclic Systems through 6-endo-ring Closures

The stereocontrolled synthesis of trans-octahydroanthracenes 3, 11a-c, and 14a-c and trans-octahydro-5aH-cycloheptanaphthalene (27) through implementation of an efficient and highly regioselective 6-endo-trig-aryl radical cyclization of the respective 2-(o-bromoaryl)-1-methylenecyclohexanes 2, 10a-c, and 13a-c and 2-(o-bromobenzyl)-1-methylenecycloheptane (41) with tri-n-butyltin hydride id described.The radical cyclization of 2-(o-bromobenzyl)-1-methylenecyclopentane (43), in contrast, produced a mixture of the cis- and trans-hexahydro-1H-benzindenes (38) and (37).