138616-63-4

Upstream product

• 186581-53-3 diazomethane 
• 3433-80-5 1-Bromo-2-bromomethyl-benzene 
• 138616-61-2 Ethyl 3-(o-bromobenzyl)-2-methyl-4-oxocyclohex-2-enecarboxylate 
• 138616-62-3 2-(o-Bromobenzyl)-3-methylcyclohex-2-en-1-one 
• 487-51-4 4-carbethoxy-3-methyl-2-cyclohexen-1-one 

Downstream Products

• 138616-64-5 (1S,2R)-2-(2-Bromo-benzyl)-1-methyl-3-methylene-cyclohexanecarboxylic acid methyl ester 

Relevant academic research and scientific papers

Regioselective Aryl Radical Cyclization. 1. Stereocontrolled Synthesis of Linearly Condensed Hydroaromatic Carbocyclic Systems through 6-endo-ring Closures

The stereocontrolled synthesis of trans-octahydroanthracenes 3, 11a-c, and 14a-c and trans-octahydro-5aH-cycloheptanaphthalene (27) through implementation of an efficient and highly regioselective 6-endo-trig-aryl radical cyclization of the respective 2-(o-bromoaryl)-1-methylenecyclohexanes 2, 10a-c, and 13a-c and 2-(o-bromobenzyl)-1-methylenecycloheptane (41) with tri-n-butyltin hydride id described.The radical cyclization of 2-(o-bromobenzyl)-1-methylenecyclopentane (43), in contrast, produced a mixture of the cis- and trans-hexahydro-1H-benzindenes (38) and (37).

A Highly Regioselective 6-endo-Aryl Radical Cyclisation: Stereocontrolled Synthesis of trans-Octahydroanthracenes

The stereocontrolled synthesis of trans-octahydroanthracenes 3, 11 and 14 through implementation of an efficient and highly regioselective 6-endo-trig-aryl radical cyclisation of the respective 2-(o-bromobenzyl)-1-methylenecyclohexanes 2, 10 and 13, with