138630-73-6Relevant articles and documents
Method for inhibiting mammalian breast carcinoma with tamoxifen, and analogs thereof, and certain naphthyl compounds
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, (2008/06/13)
The present invention provides a method of inhibiting hormone-dependent breast carcinoma in a mammal comprising administering to said mammal in need of treatment an effective amount of a first component which is a compound of formula I STR1 wherein R
Method for minimizing the uterothrophic effect of tamoxifen and tamoxifen analogs
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, (2008/06/13)
The present invention provides a method of minimizing the uterotrophic effect of non-steroidal antiestrogen compounds of formula II STR1 and wherein the variables are as defined in the specification and wherein said formula II compound is administered to
Antiestrogens. 3. Estrogen Receptor Affinities and Antiproliferative Effects in MCF-7 Cells of Phenolic Analogues of Trioxifene, phenyl>methanone
Jones, Charles D.,Blaszczak, Larry C.,Goettel, Mary E.,Suarez, Tulio,Crowell, Thomas A.,et al.
, p. 931 - 938 (2007/10/02)
Benzothiophenes 3 and 4, derived from the acrylophenone antiestrogen trioxifene (2), are characterized by high estrogen receptor (ER) affinity and low residual estrogenicity compared to tamoxifen (1a).In order to characterize further the growth supperessi