138752-87-1

Upstream product

• 950-59-4 4-hydroxy-3,5-di-tert-butylthiophenol 
• 1758-32-3 epoxy-2,3 butane 
• 7647-01-0 hydrogenchloride 

Downstream Products

• 137803-61-3 (+/-)[2S*-[[3,5-bis(1,1-dimethyl-ethyl)-4-hydroxyphenyl]thio]-1R*-methylpropoxy]acetic acid 

Relevant academic research and scientific papers

2-AMINOETHANESULFONIC ACID DERIVATIVES OF 3,5-DISUBSTITUTED-4-HYDROXY-PHENOLIC THIOETHERS

The present invention relates to compounds of the Formula I:wherein R1 and R2 are the same or different and independently represent tert-alkyl, halogen, or phenyl; Alk 1 represents straight or branched chain alkylene of 2 to 10 carbon atoms which can optionally be substituted by hydroxy, provided that said hydroxy is not attached to a carbon which is adjacent to sulfur or oxygen, X represents sulfur or oxygen, and Alk 2 represents straight or branched chain alkylene of 1 to 4 carbon atoms; and the pharmaceutically acceptable salts thereof. These compounds are specific 5-lipoxygenase inhibitors and are useful as anti-inflammatory and anti-allergy agents and in the treatment of conditions mediated by 5-lipoxygenase

Process and preparation of α-alkoxy acetic acids and their salts

A process for producing an α-alkoxy acetic acids and salts thereof which comprises reacting an alcohol of the formula STR1 wherein R1, R2 and R3 can be hydrogen, alkyl, alkoxy, halo, phenyl, substituted phenyl, or hydroxy;