138850-89-2

Upstream product

• 109429-01-8 (S)-2-(benzyloxy)-3-hydroxypropyl acetate 
• 100-39-0 benzyl bromide 
• 138850-83-6 (S)-1-O-Acetyl-2-O-benzyl-3-O-methoxymethylglycerol 
• 143516-74-9 ((E)-(R)-1-Methoxymethoxymethyl-but-2-enyloxymethyl)-benzene 

Downstream Products

• 109371-30-4 (S)-2-benzyloxy-3-(toluene-4-sulfonyloxy)-propan-1-ol 
• 96924-84-4 Phosphorochloridic acid (R)-2-benzyloxy-3-hexadecyloxy-propyl ester 2-bromo-ethyl ester 
• 91326-84-0 1-O-hexadecyl-2-O-benzyl-sn-glycero-3-phosphocholine 
• 84415-89-4 (S)-2-benzyloxy-3-hexadecyloxy-propan-1-ol 
• 138850-84-7 (S)-1-O-Tosyl-2-O-benzyl-3-O-methoxymethylglycerol 

Relevant academic research and scientific papers

Syntheses of a glycerophospholipid, C16-platelet activating factor and a palmitoyl analogue of M-5, an anti-inflammatory glyceroglycolipid

From a chiral C4-epoxide (-)-3, which is one of the synthons in our synthetic strategy for complex lipids, a glycerophospholipid C16-platelet activating factor (C16-PAF, 1) and a palmitoyl analogue (2) of an anti-inflammatory glyceroglycolipid M-5, which was previously isolated from the Okinawan marine sponge Phyllospongia foliascens, have been synthesized.

Synthesis of optically active lipopeptide analogs from the outer membrane of Escherichia coli

The synthesis of optically active lipopeptide derivatives has been accomplished by the use of chiral glycerol derivatives. Lipopeptide derivatives with (R)-glycerol moieties showed higher mitogenic activities than those with the (S)-configuration. N-2,2,2-Trichloroethoxycarbonyl lipopeptide derivatives increased mitogenic activity.