138907-79-6

Usage

Uses

Used in Medicinal Chemistry:
1-(4-Methoxyphenyl)-1H-pyrazole-4-carboxylic acid is used as a building block in the development of new pharmaceuticals for various therapeutic areas. Its unique structure allows for the modulation of biological processes, making it a valuable component in the creation of innovative drugs.
Used in Drug Development:
In the field of drug development, 1-(4-Methoxyphenyl)-1H-pyrazole-4-carboxylic acid serves as a key intermediate in the synthesis of potential drug candidates. Its presence in these compounds can contribute to their pharmacological properties, enhancing their efficacy and selectivity in treating specific diseases.
Used in Organic Synthesis:
1-(4-Methoxyphenyl)-1H-pyrazole-4-carboxylic acid is utilized as a versatile reagent in organic synthesis, enabling the creation of a wide range of organic compounds with diverse applications. Its unique functional groups facilitate various chemical reactions, broadening its utility in the synthesis of complex organic molecules.
Used in Chemical Research:
In the realm of chemical research, 1-(4-Methoxyphenyl)-1H-pyrazole-4-carboxylic acid is employed as a model compound to study the properties and reactivity of pyrazole derivatives. Its unique structure provides insights into the behavior of similar compounds, aiding in the advancement of chemical knowledge and the development of new synthetic strategies.

Upstream product

• 99984-70-0 1-(4-methoxyphenyl)-1H-pyrazole-4-carbaldehyde 
• 3471-32-7 4-Methoxyphenylhydrazine 
• 37622-90-5 4-ethoxycarbonylpyrazole 
• 5720-07-0 4-methoxyphenylboronic acid 
• 19501-58-7 4-methoxyphenylhydrazine hydrochloride 
• 15001-13-5 ethyl 5-amino-1-(4-methoxy)phenyl-1H-pyrazole-4-carboxylate 
• 696-62-8 para-iodoanisole 
• 110821-34-6 ethyl 1-(4-methoxyphenyl)-1H-pyrazole-4-carboxylate 

Relevant academic research and scientific papers

Synthesis of pyrazole-carboxamides and pyrazole-carboxylic acids derivatives: Simple methods to access powerful building blocks

Hybrid systems containing pyrazole moiety show a wide spectrum of biological activities. To access novel hybrids with pyrazole ring, in this work we synthesized twenty pyrazole-carboxylic acids and twenty pyrazole-carboxamides, using simple synthetic methods, to be used as building blocks in the development of new structures.

Design, synthesis, biological evaluation and in silico studies of pyrazole‐based nh2‐acyl oseltamivir analogues as potent neuraminidase inhibitors

Oseltamivir represents one of the most successful neuraminidase (NA) inhibitors in the current anti‐influenza therapy. The 150‐cavity of NA was identified as an additional binding pocket, and novel NA inhibitors have been designed to occupy the 150‐cavity

COMPOSITIONS AND METHODS FOR TREATING CANCER

Disclosed herein, inter alia, are compositions and methods for modulating Ras and treating cancer.

Synthesis and leishmanicidal activities of 1-(4-X-phenyl)-N′-[(4-Y- phenyl)methylene]-1H-pyrazole-4-carbohydrazides

1H-pyrazole-4-carbohydrazides were synthesized and their leishmanicidal in vitro activities and cytotoxic effects were investigated. The drugs prototypes of these new compounds (ketoconazole, benznidazole, allopurinol and pentamidine) were also tested. It

Synthesis and structure - Activity relationships of 1-phenylpyrazoles as xanthine oxidase inhibitors

A series of 1-phenylpyrazoles was evaluated for inhibitory activity against xanthine oxidase in vitro. Of the compounds prepared, 1-(3-cyano-4-neopentyloxyphenyl)pyrazole-4-carboxylic acid (Y-700) had the most potent enzyme inhibition and displayed longer-lasting hypouricemic action than did allopurinol in a rat model of hyperuricemia induced by the uricase inhibitor potassium oxonate.

3-(1-SUBSTITUTED-PYRAZOYL)-2-OXINDOLE DERIVATIVES, COMPOSITIONS AND USE

This invention relates to novel 3-(1-substituted-pyrazoyl)-2-oxindole derivatives which are inhibitors of prostaglandin H2 synthease, 5-lipoxygenase and interleukin-1 biosynthesis. The compounds of the invention are useful as inhibitors of prostaglandin H