138913-07-2

Usage

Uses

Used in Pharmaceutical Industry:
4-Pentylbenzamide is used as an intermediate in the production of pharmaceuticals for its potential biological and pharmacological properties. It plays a crucial role in the synthesis of various medicinal compounds, contributing to the development of new drugs and therapies.
Used in Organic Synthesis:
In the field of organic synthesis, 4-Pentylbenzamide serves as a key intermediate. It is utilized in the preparation of other organic compounds, showcasing its versatility and importance in chemical reactions and processes.
Used in Chemical Manufacturing:
4-Pentylbenzamide is employed as a precursor in the manufacturing of other chemicals. Its unique structure and properties make it suitable for use in the production of a wide range of chemical products, further expanding its applications across various industries.
Used in Research:
4-Pentylbenzamide is also used in research settings to study its effects on different biological systems. This allows scientists to gain a deeper understanding of its potential applications and to explore new avenues for its use in various fields, such as medicine and biotechnology.
Used in Commercial Products:
4-Pentylbenzamide can be found in some commercial products, where its unique properties contribute to the overall functionality and performance of the final product. This highlights the compound's practical applications and its ability to be integrated into various consumer goods.

Upstream product

• 628-17-1 amyl iodide 
• 619-58-9 4-iodobenzoic acid 
• 26311-45-5 4-pentylbenzoic acid 
• 49763-65-7 4-pentylbenzoyl chloride 

Downstream Products

• 1537168-36-7 2-{1-[4-methyl-2-(4-pentylphenyl)thiazol-5-yl]ethylidene}hydrazinecarboximidamide 
• 1537168-58-3 1-[4-methyl-2-(4-pentylphenyl)thiazol-5-yl]ethanone 
• 651717-77-0 4-pentylbenzothioamide 
• 1313711-78-2 methyl 4-methyl-2-(4-pentylphenyl)thiazole-5-carboxylate 
• 14333-95-0 4-pentylbenzoylformaldehyde 
• 37593-02-5 4-n-pentylacetophenone 
• 10270-29-8 p-n-pentylbenzonitrile 

Relevant academic research and scientific papers

Cross coupling reactions of organozinc iodides with solid-supported electrophiles: Synthesis of 4-substituted benzoic and 3-substituted (E)- and (Z)-propenoic acids and amides

The solid-supported iodobenzoic acid derivatives 8-10 were coupled with a range of organozinc reagents 1-4 under palladium(o) catalysis. The coupled products released by acidic cleavage with TFA were obtained in high purities after recrystallization. Anal

SUBSTITUTED AMINOALKYLAZOLES AS MALARIAL ASPARTIC PROTEASE INHIBITORS

The present invention relates to novel aminoalkylazoles acting as inhibitors of malarial protease plasmepsin II. These can be used as medicines or as constituent of medicines for the treatment of malaria infection.

Potentiation of the fosmidomycin analogue FR 900098 with substituted 2-oxazolines against Francisella novicida

A library of 33 compounds was screened for potentiation of the antibiotic FR 900098 against the Francisella tularensis surrogate Francisella novicida. From the screen a highly potent 2-oxazoline adjuvant was discovered capable of potentiating FR 900098 with a 1000-fold reduction in MIC against the Francisella sub-species F. novicida and F. philomiragia.

Discovery and characterization of potent thiazoles versus methicillin- and vancomycin-resistant Staphylococcus aureus

Methicillin- and vancomycin-resistant Staphylococcus aureus (MRSA and VRSA) infections are growing global health concerns. Structure-activity relationships of phenylthiazoles as a new antimicrobial class have been addressed. We present 10 thiazole derivatives that exhibit strong activity against 18 clinical strains of MRSA and VRSA with acceptable PK profile. Three derivatives revealed an advantage over vancomycin by rapidly eliminating MRSA growth within 6 h, and no derivatives are toxic to HeLa cells at 11 μg/mL.

ANTIMICROBIAL SUBSTITUTED THIAZOLES AND METHODS OF USE

Disclosed are compositions having activity against MRSA and/or VRSA, and methods of using the compositions to treat microbial infections.

Synthesis and Liquid Crystalline Phases of Pyridazine Derivatives II

Four more pyridazine compounds were synthesized.The compounds have a general structure R-X-Y-Z-R'; where Y is 3,6 disubstituted pyridazine ring, X and Z are either trans cyclohexyl or phenyl rings, R and R' are n-alkyl groups.The structure assignments were confirmed by carbon 13 NMR.Their liquid crystalline properties were evaluated.When both X and Z are cyclohexyl rings, the compounds have a single smectic b phase.However, if a phenyl ring is introduced into the system, the morphology becomes complicated.Keywords: synthesis, pyridazine, smectic, classification