138944-33-9Relevant academic research and scientific papers
Ring transformation mediated by Lewis acids and oxidizing agents. Synthesis of 2-methoxy-1H-imidazole from 5-aminopyrimidin-4(3H)-one
Matsuura,Ueda,Murakami,Nagai,Sakakibara
, p. 608 - 610 (1993)
Treatment of 5-aminopyrimidin-4(3H)-one (1) with Lewis acidic metal salts such as zinc chloride, zinc bromide, zinc iodide, aluminum chloride, aluminum bromide, nickel chloride, copper(I) chloride, or copper(I) iodide in the presence of oxidizing agents such as ceric ammonium nitrate, ammonium persulfate, or phenyliodine(III) diacetate in methanol gave 2-methoxy-1H-imidazole (2).
Synthesis of Imidazoles by the Oxidative Transformation of 5-Aminopyrimidinones
Matsuura, Izumi,Ueda, Taisei,Murkami, Nobutoshi,Nagai, Shin-ichi,Nagatsu, Akito,Sakakibara, Jinsaku
, p. 965 - 968 (2007/10/02)
2-Alkoxy-1H-imidazoles (2a - f, 3a, b, 4a, b) were synthesized from 5-aminopyrimidin-4(3H)-ones 1a - d by treatment with oxidative metal salts (Cu(II), Tl(III), Fe(III), Pb(IV)) in alkyl alcohols.Oxidative transformation of 5-aminouracils 5a - c by thalli
A Facile Ring Transformation of 5-Aminopyrimidin-4(3H)-one into 2-Alkoxy-1H-imidazoles in the Presence of Oxidative Metal Salts and Alkyl Alcohols
Matsuura, Izumi,Ueda, Taisei,Murakami, Nobutoshi,Nagai, Shin-ichi,Sakakibara, Jinsaku
, p. 1688 - 1689 (2007/10/02)
5-Amino-6-methyl-3-phenylpyrimidin-4(3H)-one 1 was transformed into 2-alkoxy-1H-imidazoles 2a-f by treatment with various oxidative metals salts such as CuCl2, CuBr2, Cu(NO3)2, CuSO4, Tl(NO3)3, FeCl3 and Pb(OAc)4 in alkyl alcohols.
