Chemical and Pharmaceutical Bulletin p. 608 - 610 (1993)
Update date:2022-08-11
Topics:
Matsuura
Ueda
Murakami
Nagai
Sakakibara
Treatment of 5-aminopyrimidin-4(3H)-one (1) with Lewis acidic metal salts such as zinc chloride, zinc bromide, zinc iodide, aluminum chloride, aluminum bromide, nickel chloride, copper(I) chloride, or copper(I) iodide in the presence of oxidizing agents such as ceric ammonium nitrate, ammonium persulfate, or phenyliodine(III) diacetate in methanol gave 2-methoxy-1H-imidazole (2).
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