139063-19-7Relevant articles and documents
Synthesis of sulfamide linked dinucleotide analogues
Micklefield, Jason,Fettes, Kevin J.
, p. 5387 - 5390 (1997)
Novel sulfamide [-NHSO2NH-] linked dinucleotide analogues d(TnsnT) and d(TnsnA) have been synthesised from 3'- and 5'-amino nucleosides. Treatment of these amino nucleosides with catechol sulfate results in the formation of 2-hydroxyphenyl sulf
CYCLIC DINUCLEOTIDES AS STING AGONISTS
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, (2019/07/19)
Disclosed are compounds, compositions and methods for treating of diseases, syndromes, or disorders that are affected by the modulation of STING. Such compounds are represented by Formula (I) as follows: wherein B2,X2, R2a, R2b, R2c, Z-M-Y, Y1-M1Z1, B1, X1, R1a, R1b, R1c are as defined herein.
Oligonucleotide analogs with sulfamate linkages
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, (2008/06/13)
Oligonucleotides possessing at least one sulfamate or sulfamide internucleotides linkages. These compounds can be used as specific hybridization probes to detect complementary nucleic acid sequences.
Oligonucleotides with a Nuclease-Resistant Sulfur-Based Linkage
Huie, Edward M.,Kirshenbaum, Mindy R.,Trainor, George L.
, p. 4569 - 4570 (2007/10/02)
A pair of complementary oligonucleotides with an EcoR1 recognition sequence (GATTC) bearing a novel sulfamate linkage at the cleavage site have been prepared and shown to be capable of annealing to form a stable duplex that is resistant to EcoR1 cleava