171563-34-1Relevant articles and documents
Synthesis of selenium-derivatized nucleosides and oligonucleotides for X-ray crystallography
Carrasco,Ginsburg,Du,Huang
, p. 1723 - 1734 (2001)
We report here the synthesis of nucleoside and oligonucleotide analogs containing selenium, which serves as an anomalous scattering center to enable MAD phase determination in nucleotide X-ray crystallography. We have developed a phase transfer approach t
CYCLIC DINUCLEOTIDES AS STING AGONISTS
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Page/Page column 191-193, (2019/07/19)
Disclosed are compounds, compositions and methods for treating of diseases, syndromes, or disorders that are affected by the modulation of STING. Such compounds are represented by Formula (I) as follows: wherein B2,X2, R2a, R2b, R2c, Z-M-Y, Y1-M1Z1, B1, X1, R1a, R1b, R1c are as defined herein.