139067-97-3Relevant academic research and scientific papers
A process for preparing (R) - 2-hydroxy-4-phenyl-butyric acid ethyl ester method (by machine translation)
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Paragraph 0040; 0044; 0045; 0049, (2016/10/10)
The invention provides a process for preparing (R)? 2? Hydroxy? 4? Phenyl ethyl butyrate method of, in a cheap and easily obtained benzald and pyruvic acid as a raw material, by condensation, esterification, biological enzyme-catalyzed asymmetric reduction and double bond hydrogenated four-step efficient reaction, in order to eventually 82% overall yield of optically pure target product obtained (R)? HPBE. (by machine translation)
A Free-Radical-Promoted Stereospecific Decarboxylative Silylation of α,β-Unsaturated Acids with Silanes
Zhang, Lizhi,Hang, Zhaojia,Liu, Zhong-Quan
supporting information, p. 236 - 239 (2016/01/25)
A stereospecific decarboxylative silylation of acrylic and propiolic acids with silanes was developed. This reaction represents the first example of decarboxylative C-Si bond formation and provides an efficient and convenient approach to various synthetically useful alkenyl and alkynyl organosilicon compounds through the reaction of α,β-unsaturated acids with silanes. Spin-trapping and EPR experiments support a radical addition/elimination process.
Highly enantioselective alkenylation of glyoxylate with vinylsilane catalyzed by chiral dicationic palladium(II) complexes
Aikawa, Kohsuke,Hioki, Yujta,Mikami, Koichi
supporting information; experimental part, p. 13922 - 13923 (2009/12/25)
(Chemical Equation Presented) Chiral dicationic palladium complex-catalyzed vinylation and dienylation of glyoxylate with vinylsilanes and dienylsilanes to produce highly optical active allylic alcohols has been achieved. The advantages of this reaction a
