139092-24-3Relevant academic research and scientific papers
Phosphine-functionalized magnetic nanoparticles (PFMN) as a magnetic recyclable phosphorus ligand: Preparation of its palladium(II) complex for Heck reaction of chloroarenes
Khalafi-Nezhad, Ali,Panahi, Farhad
, p. 7 - 14 (2013)
In this study, magnetic nanoparticles (MNs) were functionalized using chlorodiphenylphosphine (ClPPh2) and phosphine-functionalized magnetic nanoparticles (PFMN) as a recyclable phosphorus ligand was obtained. Also, palladium(II) complex of PFMN ligand (Pd-PFMN) was prepared and its catalytic activity was evaluated in the Heck reaction of chloroarenes. The results revealed that, this new catalyst showed high catalytic activity in the Heck reaction of chloroarenes and this can be attributed to the high reactivity of Pd complex involving phosphorus ligands and dispersible ability of MNs in solution as a high surface area support.
Antiinflammatory 4,5-diarylimidazoles as selective cyclooxygenase inhibitors
Barta, Thomas E.,Stealey, Michael A.,Collins, Paul W.,Weier, Richard M.
, p. 3443 - 3448 (2007/10/03)
The synthesis and activity of a series of 4,5-diarylimidazole analogs are described. One analog had an IC50 of 80 nM, was 6750-selective against COX-1, and demonstrated in vivo potency in the mouse air pouch model.
