139161-75-4

Usage

Uses

Used in Pharmaceutical Research and Development:
(3S,5S)-(5-Methyl-pyrrolidin-3-yl)-carbamic acid tert-butyl ester is used as a key intermediate in the synthesis of various pharmaceuticals for its potential pharmacological properties. It aids in the development of new drugs, contributing to the advancement of medicinal chemistry.
Used in Organic Synthesis:
In the field of organic synthesis, (3S,5S)-(5-Methyl-pyrrolidin-3-yl)-carbamic acid tert-butyl ester serves as a versatile building block for the creation of complex organic molecules. Its unique structure allows for various chemical reactions, facilitating the synthesis of a wide range of compounds.
Used in Agrochemicals:
(3S,5S)-(5-Methyl-pyrrolidin-3-yl)-carbamic acid tert-butyl ester is utilized in the agrochemical industry, potentially contributing to the development of new pesticides, herbicides, or other agricultural chemicals. Its application in this field may enhance crop protection and yield.
Used in Other Industrial Applications:
Beyond pharmaceuticals and agrochemicals, (3S,5S)-(5-Methyl-pyrrolidin-3-yl)-carbamic acid tert-butyl ester may also find uses in other industrial sectors. Its unique chemical properties could be harnessed for specific applications, such as in the synthesis of specialty chemicals or materials with tailored properties.

Upstream product

• 152673-19-3 (3R,5S)-1-Benzyl-5-methyl-pyrrolidin-3-ol 
• 152673-20-6 (3S,5S)-1-Benzyl-5-methyl-pyrrolidin-3-ylamine 
• 74880-19-6 (S)-1-Benzyl-5-methyl-pyrrolidin-3-ylamine 
• 152673-18-2 (S)-N-benzyl-5-methylpyrrolidin-3-one 
• 173066-70-1 (S)-3-Amino-1-benzyl-5-methyl-4,5-dihydro-1H-pyrrole-2-carbonitrile 
• 152673-17-1 (3S)-⁽³⁾-Benzyl-(cyanomethyl)aminobutanonitrile 
• 139161-74-3 (2S,4S)-4-t-butoxycarbonylamino-2-methyl-1-N-benzylpyrrolidine 

Relevant academic research and scientific papers

A practical stereoselective synthesis of (2S, 4S)-4-tert-butoxycarbonylamino-2-methylpyrrolidine

Two practical syntheses of (2S, 4S)-4-tert-butoxycarbonylamino-2-methylpyrrolidine, an important intermediate for quinolone antibacterial agents, have been developed through the combination of diastereo and enantioselective reactions starting from ethyl crotonate and L-alanine, respectively.

Quinolizinone type compounds

Antibacterial compounds having the formula STR1 and the pharmaceutically acceptable salts, esters and amides thereof, preferred examples of which include those compounds wherein A is =CR6 --; R1 is cycloalkyl of from three to eight carbon atoms or substituted phenyl; R2 is selected from the group consisting of STR2 R3 is halogen; R4 is hydrogen, loweralkyl, a pharmaceutically acceptable cation, or a prodrug ester group; R5 is hydrogen, loweralkyl, halo(loweralkyl), or --NR13 R14 ; and R6 is halogen, loweralkyl, halo(loweralkyl), hydroxy-substituted loweralkyl, loweralkoxy(loweralkyl), loweralkoxy, or amino(loweralkyl), as well as pharmaceutical compositions containing such compounds and the use of the same in the treatment of bacterial infections.

Quinobenzoxazine, antineoplastic agents

Quinobenzoxazine, derivatives of the formula STR1 as well as the pharmaceutically acceptable salts, esters, amides and prodrugs thereof are disclosed, wherein R1 is hydrogen or a carboxy-protecting group, R2 and R3 are substitutents, A is oxygen, Z is a halogen or a nitrogen-containing group, X is hydrogen, halogen or alkyl, and W is hydrogen, alkyl, amino or halogen. The compounds have potent antineoplastic activity.

Chiral quinolone intermediates

Chiral compounds having the formulae STR1 useful in the synthesis of quinolone intermediates.