
Tetrahedron Letters p. 8391 - 8394 (1995)
Update date:2022-08-02
Topics:
Qun, Li
Chu, Daniel T. W.
Raye, Kathleen
Claiborne, Akiyo
Seif, Louis
Macri, Bryan
Plattner, Jacob J.
Two practical syntheses of (2S, 4S)-4-tert-butoxycarbonylamino-2-methylpyrrolidine, an important intermediate for quinolone antibacterial agents, have been developed through the combination of diastereo and enantioselective reactions starting from ethyl crotonate and L-alanine, respectively.
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Doi:10.1039/c6nj02628a
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(1991)