152673-18-2

Basic information

• Product Name: (S)-N-benzyl-5-methylpyrrolidin-3-one
• Synonyms: (S)-N-benzyl-5-methylpyrrolidin-3-one
• CAS NO: 152673-18-2
• Molecular Weight: 189.257
• Mol File: 152673-18-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (S)-N-benzyl-5-methylpyrrolidin-3-one(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-N-benzyl-5-methylpyrrolidin-3-one(152673-18-2)
• EPA Substance Registry System: (S)-N-benzyl-5-methylpyrrolidin-3-one(152673-18-2)

Safety Data

• Hazardous Substances Data: 152673-18-2(Hazardous Substances Data)

Upstream product

• 100-52-7 benzaldehyde 
• 105-36-2 ethyl bromoacetate 
• 5303-65-1 (S)-ethyl 3-aminobutyrate 
• 152673-16-0 (S)-N-(1-chloro-2-propyl)-N-cyanomethylbenzylamine 
• 6940-80-3 (S)-N-benzylalaninol 
• 173066-70-1 (S)-3-Amino-1-benzyl-5-methyl-4,5-dihydro-1H-pyrrole-2-carbonitrile 
• 152673-17-1 (3S)-⁽³⁾-Benzyl-(cyanomethyl)aminobutanonitrile 
• 152673-15-9 (S)-N-benzyl-N-cyanomethyl-2-aminopropan-1-ol 

Downstream Products

• 139161-74-3 (2S,4S)-4-t-butoxycarbonylamino-2-methyl-1-N-benzylpyrrolidine 
• 152673-20-6 (3S,5S)-1-Benzyl-5-methyl-pyrrolidin-3-ylamine 
• 139161-75-4 (2S,4S)-4-t-Butoxycarbonylamino-2-methylpyrrolidine 
• 152673-19-3 (3R,5S)-1-Benzyl-5-methyl-pyrrolidin-3-ol 

Relevant articles and documents

A practical stereoselective synthesis of (2S, 4S)-4-tert-butoxycarbonylamino-2-methylpyrrolidine

Two practical syntheses of (2S, 4S)-4-tert-butoxycarbonylamino-2-methylpyrrolidine, an important intermediate for quinolone antibacterial agents, have been developed through the combination of diastereo and enantioselective reactions starting from ethyl crotonate and L-alanine, respectively.