152673-18-2

Upstream product

• 100-52-7 benzaldehyde 
• 105-36-2 ethyl bromoacetate 
• 5303-65-1 (S)-ethyl 3-aminobutyrate 
• 152673-17-1 (3S)-⁽³⁾-Benzyl-(cyanomethyl)aminobutanonitrile 
• 152673-15-9 (S)-N-benzyl-N-cyanomethyl-2-aminopropan-1-ol 
• 152673-16-0 (S)-N-(1-chloro-2-propyl)-N-cyanomethylbenzylamine 
• 6940-80-3 (S)-N-benzylalaninol 
• 173066-70-1 (S)-3-Amino-1-benzyl-5-methyl-4,5-dihydro-1H-pyrrole-2-carbonitrile 

Downstream Products

• 152673-19-3 (3R,5S)-1-Benzyl-5-methyl-pyrrolidin-3-ol 
• 139161-74-3 (2S,4S)-4-t-butoxycarbonylamino-2-methyl-1-N-benzylpyrrolidine 
• 152673-20-6 (3S,5S)-1-Benzyl-5-methyl-pyrrolidin-3-ylamine 
• 139161-75-4 (2S,4S)-4-t-Butoxycarbonylamino-2-methylpyrrolidine 

Relevant academic research and scientific papers

A practical stereoselective synthesis of (2S, 4S)-4-tert-butoxycarbonylamino-2-methylpyrrolidine

Two practical syntheses of (2S, 4S)-4-tert-butoxycarbonylamino-2-methylpyrrolidine, an important intermediate for quinolone antibacterial agents, have been developed through the combination of diastereo and enantioselective reactions starting from ethyl crotonate and L-alanine, respectively.

Chiral quinolone intermediates

Chiral compounds having the formulae STR1 useful in the synthesis of quinolone intermediates.