1391978-74-7

Upstream product

• 100-39-0 benzyl bromide 
• 609-67-6 2-Iodobenzoyl chloride 
• 3866-79-3 1,3-bis(p-toluenesulfonylthio)propane 
• 1391978-72-5 2-((2-azidoethyl)(benzyl)amino)isoquinoline-1,3(2H,4H)-dione 
• 1391978-70-3 N'-(2-azidoethyl)-N'-benzyl-2-iodobenzohydrazide 
• 1391978-68-9 1-(2-azidoethyl)-1-benzylhydrazine 
• 1391978-66-7 (E)-ethyl 2-(2-(2-azidoethyl)-2-benzylhydrazono)propanoate 

Downstream Products

• 1391978-76-9 2-((2-azidoethyl)(benzyl)amino)-4,4-dimethoxyisoquinoline-1,3(2H,4H)-dione 
• 1391978-78-1 4-benzyl-11,11-dimethoxy-3,4-dihydro-2H-[1,2,4]triazino[2,3-b]isoquinolin-6(11H)-one 
• 1391978-80-5 2-benzyl-3,4-dihydro-2H-[1,2,4]triazino[4,3-b]isoquinoline-6,11-dione 
• 1391978-92-9 4-benzyl-3,4-dihydro-2H-[1,2,4]triazino[2,3-b]isoquinoline-6,11-dione 

Relevant academic research and scientific papers

Synthesis of 1,2,4-triazines and the triazinoisoquinolinedione DEF ring system of noelaquinone

The intramolecular Staudinger-aza-Wittig reaction is used for a general synthesis of 1,2,5,6-tetrahydro-1,2,4-triazines, a structural motif reported for the natural product noelaquinone. The DEF moiety of noelaquinone was obtained in 13 steps and 2% overall yield, and the structure of the synthetic product was confirmed by X-ray analysis.