1392113-73-3

Basic information

• Product Name: C₅₇H₁₀₅N₅O₁₈S
• Synonyms: C₅₇H₁₀₅N₅O₁₈S
• CAS NO: 1392113-73-3
• Molecular Weight: 1180.55
• Mol File: 1392113-73-3.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: C₅₇H₁₀₅N₅O₁₈S(CAS DataBase Reference)
• NIST Chemistry Reference: C₅₇H₁₀₅N₅O₁₈S(1392113-73-3)
• EPA Substance Registry System: C₅₇H₁₀₅N₅O₁₈S(1392113-73-3)

Safety Data

• Hazardous Substances Data: 1392113-73-3(Hazardous Substances Data)

Upstream product

• 172950-21-9 di-tert-butyl ((1S,3R,4S,5S,6R)-4-(((2S,3R,4S,5S,6R)-4-((tert-butoxycarbonyl)amino)-3,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-6-(((2R,3R,5S,6R)-3-((tert-butoxycarbonyl)amino)-6-(((tert-butoxycarbonyl)methyl)-5-hydroxytetrahydro-2H-pyran-2-yl)oxy)-5-hydroxycyclohexane-1,3-diyl)dicarbamate) 
• 2079-95-0 1-tetradecanethiol 
• 220612-64-6 ((2R,3S,4S,5R,6S)-6-(((1S,2S,3R,4S,6R)-4,6-bis((tert-butoxycarbonyl)amino)-3-(((2R,3R,5S,6R)-3-((tert-butoxycarbonyl)methyl)-5-hydroxytetrahydro-2Hpyran-2-yl)oxy)-2-hydroxycyclohexyl)oxy)-4-((tert-butoxycarbonyl)amino)-3,5-dihydroxytetrahydro-2H-pyran-2-yl)methyl 2,4,6-triisopropylbenzenesulfonate 
• 32986-56-4 tobramycin 

Downstream Products

• 1392113-91-5 C₃₂H₆₅N₅O₈S 
• 1392114-09-8 C₃₂H₆₅N₅O₁₀S 

Relevant articles and documents

Amphiphilic tobramycin analogues as antibacterial and antifungal agents

In this study, we investigated the in vitro antifungal activities, cytotoxicities, and membrane-disruptive actions of amphiphilic tobramycin (TOB) analogues. The antifungal activities were established by determination of MIC values and in time-kill studie

Design of membrane targeting tobramycin-based cationic amphiphiles with reduced hemolytic activity

Tobramycin-based cationic amphiphiles differing in the chemical bond linking their hydrophobic and hydrophilic parts were synthesized and biologically evaluated. Several compounds demonstrated potent antimicrobial activities compared to the parent drug. One analogue exhibited a significant reduction in red blood cells hemolysis, demonstrating that it is possible to maintain the antimicrobial potency of these molecules while reducing their undesired hemolytic effect through chemical modifications. The Royal Society of Chemistry 2013.