139244-40-9

Basic information

• Product Name: Cytidine, N-benzoyl-2'-deoxy-5'-O-[(1,1-dimethylethyl)diphenylsilyl]-
• CAS NO: 139244-40-9
• Molecular Formula: C32H35N3O5Si
• Molecular Weight: 569.732
• Mol File: 139244-40-9.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Cytidine, N-benzoyl-2'-deoxy-5'-O-[(1,1-dimethylethyl)diphenylsilyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Cytidine, N-benzoyl-2'-deoxy-5'-O-[(1,1-dimethylethyl)diphenylsilyl]-(139244-40-9)
• EPA Substance Registry System: Cytidine, N-benzoyl-2'-deoxy-5'-O-[(1,1-dimethylethyl)diphenylsilyl]-(139244-40-9)

Safety Data

• Hazardous Substances Data: 139244-40-9(Hazardous Substances Data)

Upstream product

• 951-77-9 2'-Deoxycytidine 
• 98-88-4 benzoyl chloride 
• 4836-13-9 N₄-benzoyl-2'-deoxycytidine 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 93-97-0 benzoic acid anhydride 
• 276870-95-2 4-amino-1-((2R,4S,5R)-5-(((tert-butyldiphenylsilyl)oxy)methyl)-4-hydroxytetrahydrofuran-2-yl)pyrimidin-2(1H)-one 

Downstream Products

• 149097-52-9 diethyl N⁴-benzoyl-5'-O-tert-butyldiphenylsilyl-2'-deoxy-3'-O-phosphonomethylcytidine 
• 139244-41-0 N-{1-[5-(tert-butyl-diphenyl-silanyloxymethyl)-4-oxo-tetrahydro-furan-2-yl]-2-oxo-1,2-dihydro-pyrimidin-4-yl}-benzamide 
• 195247-28-0 3-N-benzoyl-3'-O-(9-phenylxanthen-9-yl)-2'-deoxycytidine 
• 132062-98-7 4-N-benzoyl-2'-deoxy-5'-O-phosphonomethyl-3'-O-(tetrahydro-2H-pyran-2-yl)cytidine diethyl ester 
• 132062-97-6 4-N-benzoyl-2'-deoxy-3'-O-(tetrahydro-2H-pyran-2-yl)cytidine 
• 181423-22-3 N⁴-benzoyl-1-[3-O-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)-2-deoxy-β-D-ribofuranosyl]-cytosine 
• 305819-96-9 4-N-benzoyl-1-(5-O-tert-butyldiphenylsilyl-2-deoxy-3-C-phosphono-β-D-threo-pentofuranosyl)cytosine 
• 140712-80-7 N⁴-benzoyl-3'-O-dimethoxytrityl-2'-deoxycytidine 
• 854389-81-4 {(2R,3S,5R)-5-(4-Benzoylamino-2-oxo-2H-pyrimidin-1-yl)-3-[bis-(4-methoxy-phenyl)-phenyl-methoxy]-tetrahydro-furan-2-ylmethoxymethyl}-phosphonic acid monomethyl ester 
• 181423-12-1 N⁴-benzoyl-1-[5-O-tert-butyldiphenylsilyl-3-O-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)-2-deoxy-β-D-ribofuranosyl]-cytosine 

Relevant articles and documents

NUCLEOTIDE CLEAVABLE LINKERS AND USES THEREOF

Disclosed herein, inter alia, are compounds, compositions, and methods of use thereof for sequencing a nucleic acid.

Nucleosidyl-O-methylphosphonates: A pool of monomers for modified oligonucleotides

An unique set of 5′-O- and 3′-O-phosphonomethyl derivatives of four natural 2′-deoxyribonucleosides, 1-(2-deoxy-β-D-threo- pentofuranosyl)thymine, 5′-O- and 2′-O-phosphonomethyl derivatives of 1-(3-deoxy-β-D-erythro-pentofuranosyl)thymine, and 1-(3-deoxy-β-D- threo-pentofuranosyl)thymine has been synthesized as a pool of monomers for the synthesis of modified oligonucleotides. The phosphonate moiety was protected with 4-methoxy-1-oxido-2-pyridylmethyl ester group, serving also as an intramolecular catalyst in the coupling step.

Ribosylation of pyrimidine 2'-deoxynucleosides

The previously developed method for the preparation of 2'-O-D- ribofuranosyl-nucleosides is extended to ribosylation of 2'- deoxynucleosides. The scope and limitations of this reaction are discussed.