139260-71-2

Basic information

• Product Name: 3-Pyridinecarboxylic acid, 4-[1-[5-methoxy-1-(phenylsulfonyl)-1H-indol-2-yl]ethyl]-
• CAS NO: 139260-71-2
• Molecular Formula: C23H20N2O5S
• Molecular Weight: 436.488
• Mol File: 139260-71-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-Pyridinecarboxylic acid, 4-[1-[5-methoxy-1-(phenylsulfonyl)-1H-indol-2-yl]ethyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Pyridinecarboxylic acid, 4-[1-[5-methoxy-1-(phenylsulfonyl)-1H-indol-2-yl]ethyl]-(139260-71-2)
• EPA Substance Registry System: 3-Pyridinecarboxylic acid, 4-[1-[5-methoxy-1-(phenylsulfonyl)-1H-indol-2-yl]ethyl]-(139260-71-2)

Safety Data

• Hazardous Substances Data: 139260-71-2(Hazardous Substances Data)

Upstream product

• 139260-65-4 1-(5-Methoxy-1-phenylsulphonylindol-2-yl)-1-methylfuro<3,4-c>pyridin-3(1H)-one 
• 59-67-6 nicotinic acid 
• 10400-19-8 3-pyridinecarbonyl chloride 
• 4664-08-8 cinchomeronic anhydride 
• 490-11-9 3,4-pyridinecarboxylic acid 
• 38173-40-9 4-methoxycarbonyl-3-pyridylcarbonyl chloride 
• 24202-74-2 4-(methoxycarbonyl)nicotinic acid 
• 139125-05-6 4-Acetyl-N,N-diisopropylnicotinamide 
• 139260-68-7 Methyl 3-(Diisopropylcarbamoyl)isonicotinate 

Downstream Products

• 139260-59-6 4-[1-(1-Benzenesulfonyl-5-methoxy-1H-indol-2-yl)-ethyl]-N-(3-diethylamino-propyl)-nicotinamide 
• 139260-72-3 4-[1-(1-Benzenesulfonyl-5-methoxy-1H-indol-2-yl)-ethyl]-N-(2-dimethylamino-ethyl)-nicotinamide 

Relevant articles and documents

Synthesis of 11-Amino-substituted-9-methoxy-5-methyl-6H-pyridocarbazoles

A route to 11-amino-substituted-6H-pyridocarbazoles has been studied.Thus, condensation of 2-(4-lithiopyridine-3-yl)-4,4-dimethyloxazoline with 2-acetyl-5-methoxy-1-phenylsulphonylindole led to a low yield of the expected alcohol, which upon hydrolysis gave a complex mixture.A better starting building block was 4-acetyl-N,N-diisopropylnicotinamide obtained either from N,N-diisopropyl-4-lithionicotinamide (low yield) or from pyridine-3,4-dicarboxylic anhydride, using a 4-step sequence.This compound was treated with 2-lithio-5-methoxy-1-phenylsulphonylindole, affording N,N-diisopropyl-4-nicotinamide.Hydrolysis and then reduction led to 4-nicotinic acid whose amides were cyclized by phosphorus trichlorideoxide.Finally, the title compounds were obtained by Raney-nickel reduction-elimination of the 6-phenylsulphonyl protecting group.