13941-59-8

Upstream product

• 74-85-1 ethene 
• 19578-13-3 1-(p-Chlorophenyl)-3-(4'-morpholinyl)-1-propanone 
• 28123-63-9 4-chlorobenzohydroximoyl chloride 
• 60-34-4 methylhydrazine 
• 208183-97-5 2-[3-(4-Chloro-phenyl)-prop-2-ynyloxy]-isoindole-1,3-dione 
• 3848-36-0 4-chlorobenzaldoxime 
• 33994-12-6 3-bromo-1-(4-chlorophenyl)propan-1-one 
• 108-90-7 chlorobenzene 

Downstream Products

• 623-03-0 4-Cyanochlorobenzene 
• 80815-68-5 (Z)-3-Amino-3-(4-chloro-phenyl)-propenal 
• 80815-71-0 4-(4-Chloro-phenyl)-2,5-dihydro-oxazole 

Relevant academic research and scientific papers

Transformation of arenes into 3-arylpyrazoles and 3-arylisoxazolines with β-bromopropionyl chloride, hydrazine, and hydroxylamine

Successive treatment of arenes with β-bromopropionyl chloride and AlCl3, followed by the reactions with hydrazines and Na2CO3, and then with MnO2 gave the corresponding 3-arylpyrazoles in one pot in good to moderate yields. The same successive treatment of arenes with β-bromopropionyl chloride and AlCl3, followed by the reactions with hydroxylamine and KF gave the corresponding 3-arylisoxazolines in one pot in good to moderate yields.

The preparation of 2-isoxazolines from O-propargylic hydroxylamines via a tandem rearrangement-cyclisation reaction

A method for the conversion of O-propargylic hydroxylamines into 2-isoxazolines in 60-84% yield is described. For 3-alkylpropargyl or 3-arylpropargyl hydroxylamines this was achieved by heating a methanolic solution of the hydrochloride salt in the presen

PHOTOCHEMISTRY OF 3-ARYL-2-ISOXAZOLINE

3-Phenyl-2-isoxazoline (1) was irradiated to give 4-phenyl-2-oxazoline (3), β-aminoaldehyde (14) and benzonitrile from its ?-?* singlet excited state.Several related derivatives afforded similar photoproducts on irradiation.The quantum yields of the photoreactions were dependent on the magnitudes of the singlet energies of the 2-isoxazolines. p-Cyanophenyl-2-isoxaline (1c) formed a one-to-one photoadduct (22) with benzene.