1394159-51-3Relevant academic research and scientific papers
A new synthetic route to p -methoxy-2,6-disubstituted anilines and their conversion into n-heterocyclic carbene precursors
Meiries, Sebastien,Nolan, Steven P.
, p. 393 - 398 (2014/03/21)
The development of new N-heterocyclic carbenes (NHC) is a key feature in this now mainstream research area to access novel chemical properties and reactivity that are essential for the discovery of original applications. Up to now, only a few reliable methods have proven suitable for the preparation of methoxylated anilines to ultimately access methoxylated NHC. We are pleased to report here a straightforward and scalable approach to address this matter. Georg Thieme Verlag Stuttgart. New York.
Iron-catalyzed formation of 2-aminopyridines from diynes and cyanamides
Lane, Timothy K.,D'Souza, Brendan R.,Louie, Janis
, p. 7555 - 7563 (2012/11/07)
Diynes and cyanamides undergo an iron-catalyzed [2 + 2 + 2] cycloaddition to form highly substituted 2-aminopyridines in an atom-efficient manner that is both high yielding and regioselective. This system was also used to cyclize two terminal alkynes and
