1394231-06-1

Basic information

• Product Name: diethyl 2-(6-chloro-4-(4-methoxybenzyl)-3-oxo-3,4-dihydropyrazin-2-yl)malonate
• Synonyms: diethyl 2-(6-chloro-4-(4-methoxybenzyl)-3-oxo-3,4-dihydropyrazin-2-yl)malonate
• CAS NO: 1394231-06-1
• Molecular Weight: 408.839
• Mol File: 1394231-06-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: diethyl 2-(6-chloro-4-(4-methoxybenzyl)-3-oxo-3,4-dihydropyrazin-2-yl)malonate(CAS DataBase Reference)
• NIST Chemistry Reference: diethyl 2-(6-chloro-4-(4-methoxybenzyl)-3-oxo-3,4-dihydropyrazin-2-yl)malonate(1394231-06-1)
• EPA Substance Registry System: diethyl 2-(6-chloro-4-(4-methoxybenzyl)-3-oxo-3,4-dihydropyrazin-2-yl)malonate(1394231-06-1)

Safety Data

• Hazardous Substances Data: 1394231-06-1(Hazardous Substances Data)

Upstream product

• 105-53-3 diethyl malonate 
• 393860-82-7 3,5-dichloro-1-(4-methoxybenzyl)pyrazin-2(1H)-one 

Relevant articles and documents

Alkylation of 3,5-dichloro-2(1H)-pyrazinones using malonate esters

An efficient base-promoted 3-alkylation of 3,5-dichloro-2(1H)-pyrazinones with various malonate esters is described. The method constitutes a simple example of a C-C bond forming process at the 3-position of the pyrazinone core allowing to attain 3-substituted pyrazinones in good to high yields. 3-Alkylation of 3,5-dichloro-2(1H)-pyrazinones with acetoacetic ester was accompanied by further retro-Claisen fragmentation.