1394248-99-7

Basic information

• Product Name: 1-N-ethyl-piperazinomethyl-3-[1-(4-isobutylphenyl)ethyl]-4-(3-phenyl-4-sydnonylidene)amino-1,2,4-triazol-5-thione
• Synonyms: 1-N-ethyl-piperazinomethyl-3-[1-(4-isobutylphenyl)ethyl]-4-(3-phenyl-4-sydnonylidene)amino-1,2,4-triazol-5-thione
• CAS NO: 1394248-99-7
• Molecular Weight: 574.75
• Mol File: 1394248-99-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-N-ethyl-piperazinomethyl-3-[1-(4-isobutylphenyl)ethyl]-4-(3-phenyl-4-sydnonylidene)amino-1,2,4-triazol-5-thione(CAS DataBase Reference)
• NIST Chemistry Reference: 1-N-ethyl-piperazinomethyl-3-[1-(4-isobutylphenyl)ethyl]-4-(3-phenyl-4-sydnonylidene)amino-1,2,4-triazol-5-thione(1394248-99-7)
• EPA Substance Registry System: 1-N-ethyl-piperazinomethyl-3-[1-(4-isobutylphenyl)ethyl]-4-(3-phenyl-4-sydnonylidene)amino-1,2,4-triazol-5-thione(1394248-99-7)

Safety Data

• Hazardous Substances Data: 1394248-99-7(Hazardous Substances Data)

Upstream product

• 14484-83-4 4-formyl-3-phenyl-sydnone 
• 6415-68-5 N-nitroso-N-phenylglycine 
• 508191-77-3 3-phenylsydnone 
• 62-53-3 aniline 
• 103-01-5 N-Phenylglycine 
• 15687-27-1 ibuprofen 
• 2216-92-4 N-phenylglycine ethyl ester 
• 515883-91-7 4-amino-5-[1-(4-isobutylphenyl)ethyl]-3-mercapto-(4H)-1,2,4-triazole 
• 5308-25-8 4-ethylpiperazine 
• 50-00-0 formaldehyd 
• 1394248-93-1 3-[1-(4-isobutylphenyl)ethyl]-4-(3-phenyl-4-sydnonylidene)amino-5-mercapto-1,2,4-triazole 

Relevant articles and documents

Regioselective reaction: Synthesis, characterization and pharmacological activity of some new Mannich and Schiff bases containing sydnone

A novel series of 1-substituted aminomethyl-3-[1-(4-isobutylphenyl)ethyl]- 4-(3-aryl-4-sydnonylidene) amino-1,2,4-triazol-5-thiones (9), was prepared from the 3-[1-(4-isobutylphenyl)ethyl]-4-(3-aryl-4-sydnonylidene) amino 5-mercapto-1,2,4-triazoles (8) by aminomethylation with formaldehyde and secondary amine. The structures of Schiff bases (8) and Mannich bases (9) were characterized on the basis of IR, NMR, mass spectra1 data and elemental analysis. The newly synthesized compounds were screened for their anti-inflammatory and analgesic activities. Mannich bases (9) carrying piperidine and morpholine residues showed promising anti-inflammatory and analgesic activity.