139434-68-7

Basic information

• Product Name: N-Benzoyl-2'-O-[(methylthio)methyl]-3',5'-O-[1,1,3,3-tetrakis(1-methylethyl)-1,3-disiloxanediyl]cytidine
• Synonyms: N-Benzoyl-2'-O-[(methylthio)methyl]-3',5'-O-[1,1,3,3-tetrakis(1-methylethyl)-1,3-disiloxanediyl]cytidine;TSN-013 2,-O-MethylthioMethyl-3',5'-TIPDS-4N-Benzoyl Cytidine
• CAS NO: 139434-68-7
• Molecular Formula: C₃₀H₄₇N₃O₇SSi₂
• Molecular Weight: 649.95
• Mol File: 139434-68-7.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• Density: 1.21
• CAS DataBase Reference: N-Benzoyl-2'-O-[(methylthio)methyl]-3',5'-O-[1,1,3,3-tetrakis(1-methylethyl)-1,3-disiloxanediyl]cytidine(CAS DataBase Reference)
• NIST Chemistry Reference: N-Benzoyl-2'-O-[(methylthio)methyl]-3',5'-O-[1,1,3,3-tetrakis(1-methylethyl)-1,3-disiloxanediyl]cytidine(139434-68-7)
• EPA Substance Registry System: N-Benzoyl-2'-O-[(methylthio)methyl]-3',5'-O-[1,1,3,3-tetrakis(1-methylethyl)-1,3-disiloxanediyl]cytidine(139434-68-7)

Safety Data

• Hazardous Substances Data: 139434-68-7(Hazardous Substances Data)

Usage

General Description

N-Benzoyl-2'-O-[(methylthio)methyl]-3',5'-O-[1,1,3,3-tetrakis(1-methylethyl)-1,3-disiloxanediyl]cytidine is a chemical compound composed of cytidine with a benzoyl group and a methylthiomethyl group attached to its 2'-O position and 3',5'-O position, respectively. Additionally, it contains a unique silicon-containing linker molecule, 1,1,3,3-tetrakis(1-methylethyl)-1,3-disiloxanediyl, which further modifies the structure of the cytidine molecule. N-Benzoyl-2'-O-[(methylthio)methyl]-3',5'-O-[1,1,3,3-tetrakis(1-methylethyl)-1,3-disiloxanediyl]cytidine has potential applications in organic chemistry and drug discovery due to its modified nucleoside structure and the unique properties conferred by the disiloxane linker. Further research may uncover its potential biological activities and therapeutic uses.

Upstream product

• 4546-55-8 N-benzoyladenosine 
• 67-68-5 dimethyl sulfoxide 
• 69304-43-4 1-[3,5-O-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)-β-D-ribofuranosyl]-N⁴-benzoylcytosine 
• 13089-48-0 N₄-benzoylcytidine 
• 69304-37-6 1,3-Dichloro-1,1,3,3-tetraisopropyldisiloxane 
• 79154-57-7 3',5'-O-(tetraisopropyldisiloxane-1,3-diyl)-N₆-benzoyladenosine 

Downstream Products

• 329032-86-2 2'-O-azidomethyl-N⁴-benzoyl-3',5'-O-(1,1,3,3-tetraisopropyldisilox-1,3-diyl)cytidine 
• 329032-90-8 2'-O-azidomethyl-N⁴-benzoylcytidine 
• 931386-09-3 N⁴-benzoyl-2'-O-(tert-butyldithiomethyl)cytidine 
• 929896-90-2 C₅₄H₅₉N₆O₁₂P 
• 929896-86-6 C₄₅H₄₂N₄O₁₁ 
• 929896-82-2 N⁴-benzoyl-2'-O-[[(4-nitrobenzyl)oxy]methyl]cytidine 
• 929896-79-7 C₃₆H₅₀N₄O₁₀Si₂ 
• 139434-72-3 N⁴-benzoyl-2'-O-methylthiomethylcytidine 

Relevant articles and documents

General method for the synthesis of 2′-O-carboranyl-nucleosides

The carboranyl cage is a new modifying entity for nucleosides, DNA oligonucleotides, and other biomolecules. Herein, the first reliable method for the synthesis of nucleosides modified with a carborane cluster at the 2′-position is described.

An azidomethyl protective group in the synthesis of oligoribonucleotides by the phosphotriester method

A rapid and effective method of an automatic oligoribonucleotide synthesis alternative to the phosphoramidite one was developed. This method is based on the phosphotriester approach to internucleotide bond formation under intramolecular O-nucleophilic cat

The 4-(N-dichloroacetyl-N-methylamino)benzyloxymethyl group for 2′-hydroxyl protection of ribonucleosides in the solid-phase synthesis of oligoribonucleotides

(Chemical Equation Presented) Emerging RNA-based technologies for controlling gene expression have triggered a high demand for synthetic oligoribonucleotides and have motivated the development of ribonucleoside phosphoramidites that would exhibit coupling