1394401-59-2Relevant academic research and scientific papers
Synthesis of polysubstituted cyclopenta[b]indoles via relay gold(i)/Bronsted acid catalysis
Dhiman, Seema,Ramasastry
, p. 557 - 560 (2015)
An efficient relay catalytic process involving Au(i)/Bronsted acid to access various polysubstituted cyclopentannulated indoles from easily accessible 1-(2-aminophenyl)prop-2-ynols and readily available 1,3-dicarbonyls has been developed. In an unprecedented event, the intermediate 2-indolylmethyl cations undergo the cation-Ene reaction with various 1,3-dicarbonyls followed by an intramolecular Friedel-Crafts-type reaction generating functionalized cyclopenta[b]indoles. This journal is
Cascade Skeletal Rearrangement of Gold Carbene Intermediates: Synthesis of Medium-Sized Pyrimidine-Fused Benzolactones
Hu, Xiaoping,Liu, Yuanhong,Wang, Ali,Xie, Xin
supporting information, p. 3769 - 3774 (2021/07/17)
A gold-catalyzed cyclization/cascade skeletal rearrangement of o-cyanophenylalkynones with 3-amino-benzo[d]-isoxazoles has been developed, which provides an approach for synthesizing medium-sized benzolactones. Based on the experimental results, we postul
Silver acetate catalyzed hydroamination of 1-(2-(sulfonylamino)phenyl)prop- 2-yn-1-ols to (Z)-2-methylene-1-sulfonylindolin-3-ols
Susanti, Dewi,Koh, Fujiet,Kusuma, Jeffrey Antonius,Kothandaraman, Prasath,Chan, Philip Wai Hong
, p. 7166 - 7175 (2012/10/29)
A method to prepare (Z)-2-methylene-1-sulfonylindolin-3-ols efficiently that relies on silver acetate catalyzed hydroamination of 1-(2-(sulfonylamino) phenyl)prop-2-yn-1-ols is reported. The reactions proceed rapidly at room temperature with catalyst loadings as low as 1 mol % under conditions that did not require the exclusion of air or moisture. The utility of this N-heterocyclic ring-forming strategy as a synthetic tool that makes use of unsaturated alcohols was exemplified by the conversion of the (Z)-2-methylene-1- sulfonylindolin-3-ol to examples of other members of the indole family of compounds.
