139705-74-1 Usage
Description
4-IMIDAZO[1,2-A]PYRIDIN-2-YL-PHENYLAMINE is an organic compound that serves as a crucial intermediate in the synthesis of various pharmaceuticals. It is characterized by its unique chemical structure, which includes an imidazopyridine ring fused with a phenylamine group. This structure endows it with specific properties that make it valuable in the development of new drugs.
Uses
Used in Pharmaceutical Industry:
4-IMIDAZO[1,2-A]PYRIDIN-2-YL-PHENYLAMINE is used as an intermediate for the preparation of new imidazopyridines. These imidazopyridines are developed as angiotensin antagonists, which possess antihypertensive activity. By targeting the renin-angiotensin system, these compounds can effectively manage high blood pressure and contribute to the treatment of hypertension.
As an intermediate, 4-IMIDAZO[1,2-A]PYRIDIN-2-YL-PHENYLAMINE plays a vital role in the synthesis of these angiotensin antagonists, enabling the development of novel therapeutic agents to combat hypertension and its associated health risks.
Check Digit Verification of cas no
The CAS Registry Mumber 139705-74-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,9,7,0 and 5 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 139705-74:
(8*1)+(7*3)+(6*9)+(5*7)+(4*0)+(3*5)+(2*7)+(1*4)=151
151 % 10 = 1
So 139705-74-1 is a valid CAS Registry Number.
InChI:InChI=1/C13H11N3/c14-11-6-4-10(5-7-11)12-9-16-8-2-1-3-13(16)15-12/h1-9H,14H2
139705-74-1Relevant articles and documents
1-Phenyl-: N -(benzothiazol-2-yl)methanimine derivatives as Middle East respiratory syndrome coronavirus inhibitors
Hu, Min-Qi,Li, Heng,Lin, Ying,Tang, Jie,Tang, Wei,Tong, Xian-Kun,Yang, Fan,Yu, Li-Fang,Zhang, Ying,Zuo, Jian-Ping
, p. 43299 - 43311 (2020/12/25)
Middle East respiratory syndrome coronavirus (MERS-CoV) poses a serious threat to human health, and currently there are no effective or specific therapies available to treat it. Herein a series of 1-phenyl-N-(benzothiazol-2-yl)methanimine derivatives with inhibitory activity against MERS-CoV are described. The compound 4f with a 50% inhibition concentration value of 0.09 μM is a promising inhibitor that warrants further evaluation, towards the development of potential anti-MERS-CoV drugs. This journal is
The flocculated acryloyldimethyltauric molecule ligand
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Paragraph 0420; 0689; 0690, (2016/10/08)
Provided are certain benzothiazole, imidazothiazole, imidazopyrimidine and imidazopyridine compounds, including, for example: formula (I) and pharmaceutically and physiologically acceptable salts, hydrates, and solvates thereof. Such compounds can be used as diagnostic ligands or labels of tau protein and PHF.
CYCLOPENTANECARBOXAMIDE DERIVATIVES, MEDICAMENTS CONTAINING SUCH COMPOUNDS AND THEIR USE
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, (2011/05/06)
The invention relates to cyclopentanecarboxamide derivatives of formula 1, to their use as Fatty Acid Synthase inhibitors, to methods for their therapeutic use and to pharmaceutical compositions containing them, wherein R1, R2, Rsup
