139718-50-6

Basic information

• Product Name: 1H-Indole, 5-bromo-1-(4-fluorophenyl)-3-(4-piperidinyl)-
• CAS NO: 139718-50-6
• Molecular Formula: C19H18BrFN2
• Molecular Weight: 373.268
• Mol File: 139718-50-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1H-Indole, 5-bromo-1-(4-fluorophenyl)-3-(4-piperidinyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Indole, 5-bromo-1-(4-fluorophenyl)-3-(4-piperidinyl)-(139718-50-6)
• EPA Substance Registry System: 1H-Indole, 5-bromo-1-(4-fluorophenyl)-3-(4-piperidinyl)-(139718-50-6)

Safety Data

• Hazardous Substances Data: 139718-50-6(Hazardous Substances Data)

Upstream product

• 460-00-4 1-Bromo-4-fluorobenzene 
• 1273523-86-6 C₁₉H₁₆BrFN₂*ClH 
• 352-34-1 4-fluoro-1-iodobenzene 
• 138900-24-0 1-(4-fluorophenyl)-5-bromo-1H-indole 
• 41979-39-9 4-piperidone hydrochloride 
• 489468-61-3 5-bromo-1-(4-fluorophenyl)-3-(1,2,3,6-tetrahydro-4-pyridyl)-1H-indole 

Downstream Products

• 139718-47-1 4-[5-bromo-1-(4-fluorophenyl)-1H-indol-3-yl]piperidine-1-carboxylic acid tert-butyl ester 
• 562091-75-2 1-(4-fluorophenyl)-3-(piperidin-4-yl)-5-trimethylsilyl-1H-indole 
• 562091-74-1 4-[1-(4-fluorophenyl)-5-(trimethylsilyl)-1H-indol-3-yl]piperidine-1-carboxylic acid tert-butyl ester 
• 139718-48-2 3-(1-tert-butyloxycarbonyl-4-piperidyl)-5-cyano-1-(4-fluorophenyl)-1H-indole 
• 489468-65-7 4-[1-(4-fluorophenyl)-5-(1-methylpyrazol-3-yl)-1H-indol-3-yl]piperidine-1-carboxylic acid tert-butyl ester 
• 489468-72-6 4-[1-(4-fluorophenyl)-5-(1-methylpyrazol-5-yl)-1H-indol-3-yl]piperidine-1-carboxylic acid tert-butyl ester 
• 489468-75-9 4-[1-(4-fluorophenyl)-5-(pyridin-3-yl)-1H-indol-3-yl]piperidine-1-carboxylic acid tert-butyl ester 
• 489468-73-7 4-[1-(4-fluorophenyl)-5-(1-methylimidazol-2-yl)-1H-indol-3-yl]piperidine-1-carboxylic acid tert-butyl ester 
• 489468-70-4 4-[1-(4-fluorophenyl)-5-(pyrimidin-2-yl)-1H-indol-3-yl]piperidine-1-carboxylic acid tert-butyl ester 
• 489468-71-5 4-[1-(4-fluorophenyl)-5-(pyrimidin-5-yl)-1H-indol-3-yl]piperidine-1-carboxylic acid tert-butyl ester 
• 489468-66-8 4-[1-(4-fluorophenyl)-5-(1-methylpyrazol-4-yl)-1H-indol-3-yl]piperidine-1-carboxylic acid tert-butyl ester 
• 489468-64-6 4-[1-(4-fluorophenyl)-5-(1-methyl-1,2,3-triazol-4-yl)-1H-indol-3-yl]piperidine-1-carboxylic acid tert-butyl ester 

Relevant articles and documents

Identification and synthesis of impurities formed during sertindole preparation

Sertindole (1), an atypical anti-psychotic drug is used for the treatment of schizophrenia. During the laboratory optimization and later during its bulk synthesis the formation of various impurities was observed. The impurities formed were monitored and t

Synthesis and structure-affinity relationship investigations of 5-aminomethyl and 5-carbamoyl analogues of the antipsychotic sertindole. A new class of selective α1 adrenoceptor antagonists

A new class of selective α1 adrenoceptor antagonists derived from the antipsychotic drug sertindole is described. The most potent and selective compound 1-(2-{4-[5-aminomethyl-1-(4-fluorophenyl)-1H-indol-3-yl]-1-piperidinyl} ethyl)-2-imidazolid