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2-Methoxy-4-methylpyrimidine, with the CAS number 14001-60-6, is a colorless liquid compound that is widely utilized in the field of organic synthesis. It is known for its unique chemical properties that make it a valuable component in various chemical reactions and processes.

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  • 14001-60-6 Structure
  • Basic information

    1. Product Name: 2-Methoxy-4-methylpyrimidine
    2. Synonyms: 2-METHOXY-4-METHYLPYRIMIDINE;Pyrimidine, 2-methoxy-4-methyl- (8CI,9CI)
    3. CAS NO:14001-60-6
    4. Molecular Formula: C6H8N2O
    5. Molecular Weight: 124.14
    6. EINECS: N/A
    7. Product Categories: PYRIMIDINE;Nucleotides and Nucleosides;Bases & Related Reagents;Nucleotides
    8. Mol File: 14001-60-6.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 108-110C/70mmHg
    3. Flash Point: 77.2 °C
    4. Appearance: Colourless Liquid
    5. Density: 1.068 g/cm3
    6. Vapor Pressure: 0.241mmHg at 25°C
    7. Refractive Index: 1.496
    8. Storage Temp.: Refrigerator
    9. Solubility: Dichloromethane, Ether, Ethyl Acetate, Methanol
    10. PKA: 1.69±0.20(Predicted)
    11. CAS DataBase Reference: 2-Methoxy-4-methylpyrimidine(CAS DataBase Reference)
    12. NIST Chemistry Reference: 2-Methoxy-4-methylpyrimidine(14001-60-6)
    13. EPA Substance Registry System: 2-Methoxy-4-methylpyrimidine(14001-60-6)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 14001-60-6(Hazardous Substances Data)

14001-60-6 Usage

Uses

Used in Organic Synthesis:
2-Methoxy-4-methylpyrimidine is used as a key intermediate for the synthesis of various organic compounds. Its presence in the reaction mixture allows for the formation of complex molecules with specific functional groups, which are essential in the development of pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2-Methoxy-4-methylpyrimidine is used as a building block for the development of novel drug candidates. Its unique structure and reactivity enable the creation of new molecules with potential therapeutic applications, contributing to the advancement of drug discovery and development.
Used in Agrochemical Industry:
2-Methoxy-4-methylpyrimidine is also employed in the agrochemical industry for the synthesis of new pesticides and other crop protection agents. Its versatile chemical properties allow for the design and development of innovative compounds that can effectively protect crops from pests and diseases, ensuring a stable food supply.
Used in Chemical Research:
In the field of chemical research, 2-Methoxy-4-methylpyrimidine serves as a valuable tool for understanding various reaction mechanisms and exploring new synthetic pathways. Its unique structure and reactivity make it an ideal candidate for studying the behavior of different functional groups and their interactions with other molecules, leading to a deeper understanding of organic chemistry.

Check Digit Verification of cas no

The CAS Registry Mumber 14001-60-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,4,0,0 and 1 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 14001-60:
(7*1)+(6*4)+(5*0)+(4*0)+(3*1)+(2*6)+(1*0)=46
46 % 10 = 6
So 14001-60-6 is a valid CAS Registry Number.
InChI:InChI=1/C6H8N2O/c1-5-3-4-7-6(8-5)9-2/h3-4H,1-2H3

14001-60-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-Methoxy-4-methylpyrimidine

1.2 Other means of identification

Product number -
Other names 2-Methoxy-4-methyl-pyrimidin

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:14001-60-6 SDS

14001-60-6Relevant articles and documents

One-pot etherification of purine nucleosides and pyrimidines

Kokatla, Hari Prasad,Lakshman, Mahesh K.

supporting information; experimental part, p. 4478 - 4481 (2010/12/24)

A one-pot synthesis of ethers derived from inosine, guanosine, 2′-deoxyguanosine, and pyrimidinones is described. Exposure of the heterocycle to 1H-benzotriazol-1-yloxy-tris(dimethylamino)phosphonium hexafluorophosphate (BOP) and Cs2CO3/s

PYRIMIDYLMETHYL SULFONAMIDE COMPOUNDS

-

Page/Page column 76, (2009/10/09)

The present invention relates to pyrimidin-4-ylmethyl-sulfonamides of formula (I) wherein Ra, n, R, A, Y and Het are as defined in the claims and to the N-oxides, and salts thereof and their use for combating harmful fungi, and also to compositions and seed comprising at least one such compound. The invention also relates to a process for preparing these compounds.

Study on the preparation of heteroaryl substituted enamines. A simple synthesis of heteroaryl substituted acetaldoximes from enamines

?opar, Anton,Stanovnik, Branko,Ti?ler, Miha

, p. 465 - 474 (2007/10/03)

A comparative study of the reactivity of methyl groups towards N,N-dimethylformamide dimethyl acetal and tert-butoxybis(dimethylamino)methane was carried out on methyl substituted six-membered nitrogen containing heterocycles 1 to give enamines 2, which were easily transformed to oximes by treating with hydroxylamine hydrochloride in methanol. Most of them were isolated as (E,Z)-oximes of heteroarylacetaldehyde (11), but 5-(1,2,4-triazinyl) substituted derivatives as (E,Z)-oximes of 2,5-dihydro-1,2,4-triazin-(Z)-5-ylideneacetaldehyde (11t, 11u, and 12). Oximes were finally transformed to the corresponding acetonitriles 16 and 3-(dimethylamino)acrylonitriles 17.

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