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1401067-09-1

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1401067-09-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1401067-09-1 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,4,0,1,0,6 and 7 respectively; the second part has 2 digits, 0 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1401067-09:
(9*1)+(8*4)+(7*0)+(6*1)+(5*0)+(4*6)+(3*7)+(2*0)+(1*9)=101
101 % 10 = 1
So 1401067-09-1 is a valid CAS Registry Number.

1401067-09-1Downstream Products

1401067-09-1Relevant articles and documents

A Practical Approach for Enantio- and Diastereocontrol in the Synthesis of 2,3-Disubstituted Succinic Acid Esters: Synthesis of the pan-Notch Inhibitor BMS-906024

Quesnelle, Claude A.,Gill, Patrice,Kim, Soong-Hoon,Chen, Libing,Zhao, Yufen,Fink, Brian E.,Saulnier, Mark,Frennesson, David,DeMartino, Michael P.,Baran, Phil S.,Gavai, Ashvinikumar V.

, p. 2254 - 2258 (2016/10/19)

An oxidative intermolecular enolate heterocoupling reaction was employed for the synthesis of anti-2,3-disubstituted succinic acid mono- and differentially protected diesters. Tactical approaches to access all the diastereomers are discussed. The method w

N-SUBSTITUTED BIS(FLUOROALKYL)-1,4-BENZODIAZEPINONE COMPOUNDS AS NOTCH INHIBITORS

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Paragraph 00142, (2014/04/04)

Disclosed are compounds of Formula (I): wherein: R1 is -CH2CH2CF3; R2 is -CH2CH2CF3, or -CH2CH2CH2CF3; R3 is -CH

BIS(FLUOROALKYL)-1,4-BENZODIAZEPINONE COMPOUNDS AND PRODRUGS THEREOF

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, (2014/04/03)

Disclosed are compounds of Formula (I) and/or salts thereof: wherein R1 is —CH2CH2CF3; R2 is —CH2CH2CF3 or —CH2CH2CH2CF3; R3 is H, —CH3, or Rx; R4 is H or Ry; Ring A is phenyl or pyridinyl; and Rx, Ry, Ra, Rb, y, and z are defined herein. Also disclosed are methods of using such compounds to inhibit the Notch receptor, and pharmaceutical compositions comprising such compounds. These compounds are useful in treating, preventing, or slowing the progression of diseases or disorders in a variety of therapeutic areas, such as cancer; or as prodrugs of such compounds.

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