140139-91-9Relevant academic research and scientific papers
A facile synthesis of isoindoline and Δ1-pyrrolines from chalcone and glycine by a cascade of process involving addition, in situ decarboxylation, and cyclization
Elamparuthi, Elangovan,Sarathkumar, Subramaniayan,Girija, Swaminathan,Anbazhagan, Veerappan
, p. 3992 - 3995 (2014/07/08)
In this Letter, we report a rapid one-step entry into isoindoline and Δ1-pyrrolines from chalcone. The key step in the synthesis is the addition of glycine to chalcone. In acidic medium the reaction presumably goes through aza-Michael addition,
One-pot synthesis of substituted Δ1-pyrrolines through the Michael addition of nitroalkanes to chalcones and subsequent reductive cyclization in aqueous media
Liang, Yongjiu,Dong, Dewen,Lu, Yumei,Wang, Yan,Pan, Wei,Chai, Yanyan,Liu, Qun
, p. 3301 - 3304 (2008/09/17)
A facile and efficient one-pot synthesis of substituted Δ1-pyrrolines in aqueous media has been developed. Upon treatment with aqueous sodium hydroxide in N,N-dimethylformamide, a range of chalcones underwent room temperature Michael addition r
