85142-29-6

Upstream product

• 956-04-7 3-(4-chlorophenyl)-1-phenylprop-2-en-1-one 
• 75-52-5 nitromethane 
• 104-88-1 4-chlorobenzaldehyde 
• 706-07-0 1-chloro-4-(2-nitrovinyl)benzene 
• 98-86-2 acetophenone 
• 70-11-1 α-bromoacetophenone 
• 24721-26-4 4-chlorochalcone 

Downstream Products

• 861293-45-0 2-bromo-3-(4-chloro-phenyl)-4-nitro-1-phenyl-butan-1-one 
• 321575-57-9 (R)-phenyl 3-(4-chlorophenyl)-4-nitrobutanoate 
• 140139-91-9 3-(4-chlorophenyl)-5-phenyl-3,4-dihydro-2H-pyrrole 
• 1398057-39-0 4-(4-chlorophenyl)-2-phenyl-1H-pyrrole 
• 861777-32-4 4-bromo-4-(4-chloro-phenyl)-3-nitro-1-phenyl-butan-1-one 
• 861293-47-2 4-(4-chloro-phenyl)-4-hydroxy-3-nitro-1-phenyl-butan-1-one 
• 871886-78-1 [2-(4-chloro-phenyl)-3-nitro-cyclopropyl]-phenyl ketone 
• 119492-84-1 2-phenyl-5-(p-chlorophenyl)furan 
• 123632-35-9 (R)-(-)-4-(4-chlorophenyl)pyrrolidin-2-one 
• 123632-31-5 (S)-(+)-4-(4-chlorophenyl)pyrrolidin-2-one 
• 63701-56-4 (+)-Baclofen hydrochloride 
• 63701-55-3 (R)-(-)-baclofen hydrochloride 
• 85657-99-4 2-phenyl-4-(4-chlorophenyl)furan 

Relevant academic research and scientific papers

Synthesis and photophysical properties of monomeric and dimeric halogenated aza-BODIPYs

In this study, the effects of incorporation of halogen atoms at different positions and dimerization on the photophysical properties of the aza-BODIPYs were investigated. Aza-BODIPY derivative carrying chlorine atoms on the para-position of the distal phe

Enantioselective addition of aryl ketones and acetone to nitroalkenes organocatalyzed by carbamate-monoprotected cyclohexa-1,2-diamines

Enantiomerically pure carbamate-monoprotected trans-cyclohexane-1,2-diamines are used as chiral organocatalysts for the addition of aryl ketones and acetone to nitroalkenes to give enantioenriched β-substituted γ-nitroketones. The reaction was performed i

An active and selective heterogeneous catalytic system for Michael addition

Potassium fluoride doped natural zeolite was found to be an efficient and selective solid base catalyst for 1,4-Michael addition. The catalyst is easily prepared and the workup procedure simplified by simple filtration. All products were obtained in high

Efficient microwave activation of hydrotalcite clays in Michael addition under solvent-free conditions

Microwave irradiation has been successfully utilized for the first time for the activation of unmodified hydrotalcites (HTs, a basic anionic clay), in the Michael addition reaction between enones and active methylenic compounds under solventless condition

Highly enantioselective synthesis of γ-nitro heteroaromatic ketones in a doubly stereocontrolled manner catalyzed by bifunctional thiourea catalysts based on dehydroabietic amine: A doubly stereocontrolled approach to pyrrolidine carboxylic acids

A new class of dehydroabietic amine-substituted primary amine-thiourea bifunctional catalysts were designed and synthesized. The doubly stereocontrolled organocatalytic conjugate addition of a variety of heterocycles-bearing ketones to nitroalkenes was in

Natural phosphate modified with lithium nitrate: A new efficient catalyst for the construction of carbon-carbon, carbon-sulfur, and carbon-nitrogen bonds

The addition of small amounts of lithium nitrate to natural phosphate followed by calcination gives a new catalyst Li/NP (weight ratio LiNO3/NP = 1/15). This material showed catalytic activity in the Michael addition of amines, mercaptans, and active methylene compounds to chalcone derivatives with high yields under mild reaction conditions. Li/NP is used as the catalyst for a facile synthesis of -amino acids, -sulfur acids, and 4 H-chromenes under heterogeneous conditions. The usual, undesirable byproducts from the Michael condensation such as 1,2-addition, bis-addition, and polymerization compounds are not observed with this method. The work-up procedure is simplified by simple filtration with the use of Li/NP.

One-pot synthesis of substituted Δ1-pyrrolines through the Michael addition of nitroalkanes to chalcones and subsequent reductive cyclization in aqueous media

A facile and efficient one-pot synthesis of substituted Δ1-pyrrolines in aqueous media has been developed. Upon treatment with aqueous sodium hydroxide in N,N-dimethylformamide, a range of chalcones underwent room temperature Michael addition r

Natural phosphate doped with potassium fluoride: Efficient catalyst for the construction of a carbon-carbon bond

Natural phosphate-doped catalyst was found to be an efficient, environmentally attractive, and selective solid base catalyst for 1,4-Michael addition. The products of undesirable side reactions resulting from 1,2-adddition, polymerization, and bis-additio

Samarium(III) iodide promoted three-component coupling reactions of aldehydes, α-haloketones, and active methylene or methyl compounds

In the presence of samarium(III) iodide, the reaction of aldehydes, α-haloketones with malononitrile, ethylcyanoacetate or nitromethane proceeded very efficiently and furnished moderate to high yields of adducts.

Michael addition catalyzed by potassium hydroxide under ultrasound

Michael addition of chalcone with active methylene compound such as diethyl malonate, nitromethane and ethyl acetoacetate catalyzed by potassium hydroxide in anhydrous ethanol results Michael adducts in 75-98% yield under ultrasound irradiation in 25-90 m