1401688-33-2Relevant academic research and scientific papers
4-Substituted-2-phenylquinazolines as inhibitors of BCRP
Juvale, Kapil,Wiese, Michael
, p. 6766 - 6769,4 (2012/12/12)
We investigated several 2-phenylquinazolines with different substitutions at position 4 for their BCRP inhibition. Compounds with phenyl ring attached via an amine-containing linker at position 4 were found to be potent inhibitors of BCRP. In general compounds with meta substitution of phenyl ring at position 4 were found to have higher inhibitory effect, compound 12 being the most potent and selective towards BCRP.
