140201-75-8Relevant academic research and scientific papers
Facile access to versatile polyaromatic building blocks: Selectively protected benzocyclobutenedione derivatives via regioselective [2 + 2] cycloaddition of α-alkoxybenzyne and ketene silyl acetal
Hamura, Toshiyuki,Hosoya, Takamitsu,Yamaguchi, Hiroki,Kuriyama, Yokusu,Tanabe, Mitsujiro,Miyamoto, Makoto,Yasui, Yoshizumi,Matsumoto, Takashi,Suzuki, Keisuke
, p. 3589 - 3604 (2007/10/03)
A facile, divergent access to highly oxygenated benzocyclobutene derivatives was developed via the regioselective [2 + 2] cycloaddition of α-alkoxybenzynes and ketene silyl acetals. The cycloadducts could be converted to selectively protected alkoxybenzocyclobutenediones, an attractive class of compounds for the synthesis of polyaromatic compounds. As one possible application, divergent access to a regioisomer pair of sulfonylphthalides for the Hauser approach to polyaromatic compounds is described.
A Facile Route to 3a,8a-Dihydrofurobenzofurans.
Holzapfel, Cedric W.,Williams, D. Bradley G.
, p. 8555 - 8564 (2007/10/02)
Consecutive employment of palladium-catalysis and samarium(II)iodide-induced radical chemistry allows access to analogues of the ABC enol ether tricycle of aflatoxin B1 (1).The Pd-assisted coupling of tributylstannyl ethers of various 2-iodophenols with 2
Total synthesis of the gilvocarcins
Hosoya, Takamitsu,Takashiro, Eiji,Matsumoto, Takashi,Suzuki, Keisuke
, p. 1004 - 1015 (2007/10/02)
Convergent total syntheses of the aryl C-glycoside antibiotics gilvocarcin M (1a) and gilvocarcin V (1b) have been accomplished. Key steps include (1) contrasteric coupling of D-fucofuranosyl acetate 27 with iodophenol 26, which was achieved by employing
