140241-74-3Relevant academic research and scientific papers
Cross-dehydrogenative coupling between enamino esters and ketones: Synthesis of tetrasubstituted pyrroles
Zhao, Miao,Wang, Fen,Li, Xingwei
, p. 1412 - 1415 (2012/05/04)
Tetrasubstituted pyrroles have been synthesized via the cross-dehydrogenative coupling between enamino esters and acetone. Silver carbonate proved to be an effective oxidant, and no transition metal catalyst is necessary.
Regioselectivity in the 1,3-dipolar cycloaddition of muenchnones with two electrophilic alkynes. Attempt of rationalization.
Texier, F.,Mazari, M.,Yebdri, O.,Tonnard, F.,Carrie, R.
, p. 962 - 967 (2007/10/02)
The 1,3-dipolar cycloaddition reaction of several unsymmetrically substituted muenchnones with methyl propiolate 3a and with methyl 3-phenylpropiolate 3b has been examined.The reaction generally proceeds with formation of mixtures of both possible regioisomeric pyrroles.The dipolarophile 3b is more selective than 3a in accordance with the literature.Sustmann's variation-perturbation theory could not account for the observed regioselectivities, this theory gives correct predictions with alkenes as we have shown recently. 1,3-cycloaddition / muenchnones / pyrroles / regioselectivity
