1402823-89-5Relevant academic research and scientific papers
Lewis acid mediated (3 + 2) cycloadditions of donor-acceptor cyclopropanes with heterocumulenes
Goldberg, Alexander F. G.,O'Connor, Nicholas R.,Craig, Robert A.,Stoltz, Brian M.
, p. 5314 - 5317,4 (2012/12/12)
Isocyanates, isothiocyanates, and carbodiimides are effective substrates in (3 + 2) cycloadditions with donor-acceptor cyclopropanes for the synthesis of five-membered heterocycles. These reactions exhibit a broad substrate scope, high yields, and well-defined chemoselectivity. Discussed herein are the implications of Lewis acid choice on the stereochemical outcome and the reaction mechanism.
Lewis acid mediated (3 + 2) cycloadditions of donor-acceptor cyclopropanes with heterocumulenes
Goldberg, Alexander F. G.,O'Connor, Nicholas R.,Craig, Robert A.,Stoltz, Brian M.
, p. 5314 - 5317 (2013/01/15)
Isocyanates, isothiocyanates, and carbodiimides are effective substrates in (3 + 2) cycloadditions with donor-acceptor cyclopropanes for the synthesis of five-membered heterocycles. These reactions exhibit a broad substrate scope, high yields, and well-defined chemoselectivity. Discussed herein are the implications of Lewis acid choice on the stereochemical outcome and the reaction mechanism.
