140409-01-4

Upstream product

• 128540-55-6 Acetic acid (R)-1-cyano-3-cyclohexyl-2-isopropoxycarbonylamino-propyl ester 
• 144465-90-7 (3R,4S)-3-Triisopropylsilyloxy-4-(cyclohexylmethyl)-2-azetidinone 
• 128540-55-6 2-acetoxy-4-cyclohexyl-3-(isopropoxycarbonylamino) butyronitrile 
• 143-33-9 sodium cyanide 
• 126832-06-2 N-((R)-2-Cyclohexyl-1-formyl-ethyl)-benzamide 
• 129593-16-4 N-benzoyl-D-cyclohexylalaninol 
• 129593-17-5 Boc-D-cyclohexylalaninol 
• 144465-85-0 (3R,4S)-4-(Cyclohexylmethyl)-1-(4-methoxyphenyl)-3-triisopropylsilyloxy-2-azetidinone 
• 339161-01-2 (2S,3R,5R,6S)-3-cyclohexylmethyl-5,6-diphenylmorpholine-2-carboxylic acid 
• 129397-33-7 N-(4-Methoxyphenyl)cyclohexylacetaldimine 
• 339160-95-1 (3R,5R,6S)-2-acetoxy-3-cyclohexylmethyl-5,6-diphenyl-morpholine-4-carboxylic acid benzyl ester 
• 339160-97-3 (3R,5R,6S)-2-cyano-3-cyclohexylmethyl-5,6-diphenylmorpholine-4-carboxylic acid benzyl ester 

Downstream Products

• 115131-72-1 isopropyl (2S,3S)-3-amino-4-cyclohexyl-2-hydroxybutyrate hydrochloride 
• 126832-10-8 (4S,5S)-4-(cyclohexylmethyl)-5-(isopropoxycarbonyl)-2-oxazolidinone 
• 140462-46-0 methyl (2S,3S)-2-acetoxy-3-acetylamino-4-cyclohexylbutyrate 
• 140462-45-9 methyl (2R,3S)-2-acetoxy-3-acetylamino-4-cyclohexylbutyrate 
• 128053-57-6 isopropyl (2S,3S)-3-<-L-histidyl>amino>-4-cyclohexyl-2-hydroxybutyrate 
• 276888-52-9 (2RS,3S)-3-tert-butyloxycarbonylamino-4-cyclohexyl-2-hydroxybutyric acid 
• 129704-26-3 isopropyl (2R,3R)-3-amino-4-cyclohexyl-2-hydroxybutyrate hydrochloride 
• 128053-56-5 isopropyl (2R,3R)-3-<-L-histidyl>amino>-4-cyclohexyl-2-hydroxybutyrate 

Relevant academic research and scientific papers

Stereocontrolled asymmetric synthesis of α-hydroxy-β-amino acids. A stereodivergent approach

The stereocontrolled asymmetric synthesis of α-hydroxy-β-amino acids has been investigated via the Lewis acid-promoted cyanation of (5R,6S)-2-acetoxy-4-(benzyloxycarbonyl)-5, 6-diphenyl-2,3,5,6-tetrahydro-4H-1,4-oxazines with trimethylsilyl cyanide. Base-

A Practical Synthesis of threo-3-Amino-2-hydroxycarboxylic Acids

An expeditious synthesis of (2R,3S)-3-amino-4-cyclohexyl-2-hydroxybutyric acid (2) and (2S,3R)-3-amino-2-hydroxy-4-phenylbutyric acid (4), the key components of the renin inhibitor (1) and bestatin (3), respectively, have been accomplished by featuring hi

New and efficient routes to norstatine and its analogs with high enantiomeric purity by β-Lactam Synthon Method

Norstatine and its analogs, i.e., 3-amino-2-hydroxyalkanoic acids, with high enantiomeric purity are obtained through effecient asymmetric synthesis of 3-silyloxy-β-lactams by chiral enolate - imine cyclocondensation, followed by hydrolysis.

An Expeditions Synthesis of the (2R,3S)- and (2S,3R)-3-Amino-2-hydroxy-carboxylic Acids, the Key Components of a Renin Inhibitor and Bestatin, from (S)- and (R)-Phenylalanine

The title synthesis could be achieved by featuring highly diastereoselective formation of a cyanohydrin acetate from an aldehyde under the phase-transfer conditions.

Orally Potent Human Renin Inhibitors Derived from Angiotensinogen Transition State: Design, Synthesis, and Mode of Interaction

A three-dimensional structure of the complex of human renin and the scissile site P4 Pro to P1' Val of angiotensinogen was deduced in order to design potent human renin inhibitors rationally.On the basis of this structure, an orally

MORPHOLINE CONTAINING AMINO ACID DERIVATIVES

Amino acid derivatives represented by formula STR1 wherein His represents an L-histidyl group, X represents a straight or branched alkoxy group having 1 to 7 carbon atoms, a straight or branched alkylamino group having 1 to 7 carbon atoms, a cycloalkyloxy