1404530-76-2

Upstream product

• 2393-23-9 4-methoxy-benzylamine 
• 1404530-74-0 3-(1-{6-[tert-butoxycarbonyl-(4-methoxybenzyl)amino]pyridazin-3-yl}-5-methyl-1H-pyrazol-4-yl)-3-oxopropionic acid ethyl ester 
• 75-03-6 ethyl iodide 
• 1404530-70-6 1-[6-(4-methoxybenzylamino)pyridazin-3-yl]-5-methyl-1H-pyrazole-4-carboxylic acid 
• 1404530-71-7 1-{6-[tert-butoxycarbonyl-(4-methoxybenzyl)amino]pyridazin-3-yl}-5-methyl-1H-pyrazole-4-carboxylic acid 
• 1404530-67-1 1-[6-(4-methoxybenzylamino)pyridazin-3-yl]-5-methyl-1Hpyrazole-4-carboxylic acid ethyl ester 

Relevant academic research and scientific papers

DERIVATIVES OF N-[(1H-PYRAZOL-1-YL)ARYL]-1H-INDOLE OR 1H-INDAZOLE-3-CARBOXAMIDE, PREPARATION THEREOF AND APPLICATIONS THEREOF IN THERAPEUTICS

The present invention relates to compounds corresponding to formula (I): in which: A represents a divalent aromatic radical; X represents a —CH— group or a nitrogen atom; R1 represents a (C1-C4)alkyl or a (C1-C4)alkoxy; R2 represents a group Alk; R3 represents a hydroxyl or a group —NR7R8; R4 represents a hydrogen atom, a halogen atom, a cyano, a phenyl, a group Alk, a group OAlk or a group —NR9R10; R5 represents a hydrogen atom, a halogen atom or a group Alk; R6 represents a hydrogen atom, a halogen atom, a cyano, a group —COOAlk or a —CONH2 group.

DERIVATIVES OF N- [(1H-PYRAZOL-1-YL) ARYL] - 1H - INDOLE OR 1H - INDAZOLE - 3 - CARBOXAMIDE, THEIR PREPARATION AND THEIR USE AS P2Y12 ANTAGONISTS

The present invention relates to compounds corresponding to formula (I) and their use as P2Y12 antagonists for the treatment of cardiovascular diseases.