1404575-81-0Relevant academic research and scientific papers
α-Halogenation as a Strategy to Functionalize Cyclohexa-2,4-dienones
Chittimalla, Santhosh Kumar,Koodalingam, Manikandan,Gadi, Vinod Kumar,Anaspure, Prasad
supporting information, p. 475 - 480 (2017/02/24)
A facile pyridine-mediated α-halogenation approach to functionalize cyclohexa-2,4-dienones is developed. A range of reactions, including organometallic coupling protocols, have been applied on these newly obtained halogenated cyclohexa-2,4-dienones, and the results are presented herein.
Unanticipated participation of HCl in nucleophilic chlorination reaction: Expedient route to meta chlorophenols
Chittimalla, Santhosh Kumar,Bandi, Chennakesavulu
supporting information, p. 15 - 19 (2015/12/23)
o-Quinone monoketals participated in a 1,4-addition reaction with HCl furnishing m-chlorophenols in high yields. Several readily available o-quinone monoketals were selected to display the generality of this serendipitous and unprecedented reaction and the results are presented herein.
A detour route for meta functionalization of phenols
Chittimalla, Santhosh Kumar,Kuppusamy, Rajesh,Bandi, Chennakesavulu
, p. 1991 - 1996 (2014/11/08)
Cyclohexadienones participate in a two-step procedure, a Michael addition followed by aromatization, providing hitherto difficult-to-synthesize meta-functionalized phenol derivatives in good yield. Application of the developed approach is exemplified by synthesizing C-aryl acetophenones, C-aryl glycines, and elemicin - an allylphenol natural product. Georg Thieme Verlag Stuttgart · New York.
[3+2] Cycloaddition of masked o-benzoquinones with azomethine ylides
Chittimalla, Santhosh Kumar,Kuppusamy, Rajesh,Chakrabarti, Anjan
experimental part, p. 1901 - 1906 (2012/09/22)
A simple and efficient access to highly functionalized isoindolone derivatives via a [3+2] cycloaddition process between in situ generated azomethine ylides with various stable (isolable) masked o-benzoquinones is described. This approach allows a rapid and general synthesis of isoindolones with substituents to further manipulate and elaborate the structural complexity. Georg Thieme Verlag Stuttgart · New York.
