14064-12-1Relevant articles and documents
3-(1H-PYRAZOL-4-YL)PYRIDINE ALLOSTERIC MODULATORS OF M4 MUSCARINIC ACETYLCHOLINE RECEPTOR
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Page/Page column 60, (2020/05/28)
Provided are cinnolinyl and quinolinyl pyrazol-4-yl-pyridine compounds which are allosteric modulators of the M4 muscarinic acetylcholine receptor, compositions comprising said compounds, and uses of said compounds in the treatment or prevention of diseases in which M4 muscarinic acetylcholine receptors are involved, especially neurological and psychiatric disorders and diseases.
Synthesis of the novel analogues of dysidiolide and their structure-activity relationship
Takahashi, Masato,Dodo, Kosuke,Sugimoto, Yoshikazu,Aoyagi, Yoshimi,Yamada, Yuji,Hashimoto, Yuichi,Shirai, Ryuichi
, p. 2571 - 2574 (2007/10/03)
The novel analogues of natural cdc25A inhibitor dysidiolide were synthesized. To investigate the structure-activity relationship, the inhibitory activity to enzyme and cell cycle was examined. (C) 2000 Elsevier Science Ltd.