1407149-95-4Relevant academic research and scientific papers
The Isomerization of Allylrhodium Intermediates in the Rhodium-Catalyzed Nucleophilic Allylation of Cyclic Imines
Hepburn, Hamish B.,Lam, Hon Wai
, p. 11605 - 11610 (2014)
Allylrhodium species generated from potassium allyltrifluoroborates can undergo isomerization by 1,4-rhodium(I) migration to give more complex isomers, which then react with cyclic imines to provide products with up to three new stereochemical elements. High enantioselectivities are obtained using chiral diene-rhodium complexes. Rhodium dance: Allylrhodium species generated from potassium allyltrifluoroborates can undergo isomerization by a 1,4-rhodium(I) migration to give more complex isomers, which then react with cyclic imines to provide products with up to three new stereochemical elements. High enantioselectivities are obtained with chiral diene-rhodium complexes.
A palladium-catalyzed enantioselective addition of arylboronic acids to cyclic ketimines
Yang, Guoqiang,Zhang, Wanbin
supporting information, p. 7540 - 7544 (2013/07/26)
Sly as Nicox: A palladium-catalyzed addition of arylboronic acids to ketimines has been developed to efficiently provide products in up to 99 % yield and 96 % ee. The reactions could be run under aerobic conditions and with unpurified trifluoroethanol (TFE). A pyrrolidine compound bearing a chiral α-tertiary amine was synthesized in several steps without loss of enantioselectivity. TFA=trifluoroacetate. Copyright
