14080-15-0Relevant academic research and scientific papers
α-zirconium sulfophenylphosphonate as a catalyst for the synthesis of 3,4-dihydropyrimidin-2(1H)-one derivatives under solvent free conditions
Rosati, Ornelio,Curini, Massimo,Montanari, Francesca,Nocchetti, Morena,Genovese, Salvatore
, p. 850 - 853 (2011)
3,4-Dihydropyrimidin-2(1H)-one derivatives were synthesized using layered α-zirconium sulfophenylphosphonate as a recyclable heterogeneous catalyst. Several classes of reagents, such as functionalized aromatic and aliphatic aldehydes, β-dicarbonyl derivat
A revision of the biginelli reaction under solid acid catalysis. Solvent-free synthesis of dihydropyrimidines over montmorillonite KSF
Bigi, Franca,Carloni, Silvia,Frullanti, Bettina,Maggi, Raimondo,Sartori, Giovanni
, p. 3465 - 3468 (1999)
The reaction of aldehydes, β-dicarbonyl compounds and urea (Biginelli reaction) has been performed over solid acid catalysis, under solventless conditions or in water affording dihydropyrimidines in good yield and selectivity.
An electrochemical off-on method for pyrimidin-2(1: H)-one synthesis via three-component cyclization
Kong, Yanyan,Li, Yabo,Huang, Mengmeng,Kim, Jung Keun,Wu, Yangjie
supporting information, p. 4495 - 4498 (2019/08/21)
A green and simple 'one-pot' electrochemical off-on approach to synthesize pyrimidin-2(1H)-ones was realized without any catalyst, oxidant and toxic reagent. The desired products were obtained in moderate to good yields after the stepwise 'one-pot' reacti
Microwave assisted solvent-free one pot biginelli synthesis of dihydropyrimidinone compounds on melamine-formaldehyde as a solid support
Rezaei, Ramin,Mohammadi, Mohammad Kazem,Khaledi, Adiba
, p. 4588 - 4590 (2013/06/27)
An effective one-pot synthesis of dihydropyrimidinonoes using Melamine-formaldehyde resin supported H+ (MFRH) as an inexpensive and readily available reagent through Biginelli condensation reaction of aldehyde, 1,3-dicarbonyl compounds and (thio)urea in c
Solvent-free and catalyst-free Biginelli reaction to synthesize ferrocenoyl dihydropyrimidine and kinetic method to express radical-scavenging ability
Wang, Rui,Liu, Zai-Qun
experimental part, p. 3952 - 3958 (2012/06/18)
Benzoyl and ferrocenoyl 3,4-dihydropyrimidin-2(1H)-ones (-thiones) (DHPMs) were synthesized in modest yields via catalyst-free and solvent-free Biginelli condensation of 1-phenylbutane-1,3-dione or 1-ferrocenylbutane-1,3-dione, hydroxyl benzaldehyde, and
Synthesis of Biginelli compounds using cobalt hydrogen sulfate
Memarian, Hamid Reza,Ranjbar, Mahnaz
experimental part, p. 522 - 527 (2012/01/05)
Efficient synthesis of various 2-oxo(thioxo)-1,2,3,4-tetrahydropyrimidines containing acetyl, carboethoxy, carbomethoxy and carboxamide groups on 5-position of the M-substituted and ATL-unsubstituted heterocyclic ring was achieved using cobalt hydrogen su
Tributyl borate mediated biginelli reaction: A facile microwave-assisted green synthetic strategy toward dihydropyrimidinones
Ranjith, Choorikkat,Srinivasan,Vijayan
experimental part, p. 288 - 290 (2010/06/18)
Exploitation of a new boron-based catalyst, tributyl borate, for the formation of dihydropyrimidinones under solvent-free microwave-assisted conditions is described. The method is a simple, easy, fast, cost effective, and potentially green protocol for th
One-pot synthesis of dihydropyrimidinones by dodecylphosphonic acid as solid Bronsted acid catalyst under solvent-free conditions via Biginelli condensation
Ghassamipour,Sardarian
experimental part, p. 237 - 242 (2010/11/02)
Dodecylphosphonic acid is a solid Bronsted acid that catalyzes efficiently the preparation of dihydropyrimidinones by Biginelli condensation under solvent-free conditions. This protocol offers several advantages including high yields, short reaction times
Environmentally benign aqueous zinc tetrafluoroborate-catalyzed one-pot biginelli condensation at room temperature
Kundu,Majee,Hajra
experimental part, p. 408 - 412 (2009/12/24)
A trace amount (0.6 mole % with respect to aldehyde or 1,3-dicarbonyl compound) of an aqueous solution of zinc tetrafluoroborate has been used as a mild, efficient and almost neutral catalyst for a one-pot three component condensation of aldehydes, 1,3-di
Cation exchange resin (Indion 130): An efficient, environment friendly and recyclable heterogeneous catalyst for the biginelli condensation
Pansuriya, Akshay M.,Savant, Mahesh M.,Bhuva, Chirag V.,Kapuriya, Naval,Singh, Jyoti,Naliapara, Yogesh T.
experimental part, p. 619 - 623 (2010/06/17)
Ion exchange resin catalyzed multicomponent Biginelli reaction is studied for the synthesis of 3,4-dihydropyrimidin-2-ones. Among the various solid acid catalysts Indion-130 was found to be most efficient, recyclable and environmentally benign heterogeneo
