A revision of the biginelli reaction under solid acid catalysis. Solvent-free synthesis of dihydropyrimidines over montmorillonite KSF

DOI: 10.1016/S0040-4039(99)00424-4

Source and publish data:

Tetrahedron Letters p. 3465 - 3468 (1999)

Update date:2022-08-17

Topics:

Authors:

Bigi, Franca

Carloni, Silvia

Frullanti, Bettina

Maggi, Raimondo

Sartori, Giovanni

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Article abstract of DOI:10.1016/S0040-4039(99)00424-4

The reaction of aldehydes, β-dicarbonyl compounds and urea (Biginelli reaction) has been performed over solid acid catalysis, under solventless conditions or in water affording dihydropyrimidines in good yield and selectivity.

Full text of DOI:10.1016/S0040-4039(99)00424-4

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