140844-90-2

Upstream product

• 140844-83-3 (4S)-hydroxy-6-phenyl-5-hexynoic acid methyl ester 
• 140844-83-3 4-hydroxy-6-phenyl-5-hexynoic acid methyl ester 
• 140844-87-7 (R,Z)-6-t-butyldimethylsilyloxy-1-phenyl-1-hexen-3-ol 
• 140844-84-4 (-)-(R)-γ-(2-phenylethynyl)-γ-butyrolactone 
• 59700-95-7 (E)-(R)-6-Phenyl-hex-5-ene-1,4-diol 
• 140844-89-9 (3R)-6-t-butyldimethylsilyloxy-1,2-epoxy-1-phenylhexane-3-ol 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 59700-84-4 4-oxo-6-phenyl-5-hexynoic acid methyl ester 
• 6738-06-3 phenylethynylmagnesium bromide 
• 77-76-9 2,2-dimethoxy-propane 

Downstream Products

• 140844-91-3 (4R,5R)-3-(2,2-dimethyl-5-phenylmethyl-1,3-dioxolan-4-yl)propan-1-ol 
• 140924-18-1 (4R,5S)-3-(2,2-dimethyl-5-phenylmethyl-1,3-dioxolan-4-yl)propan-1-ol 
• 125225-54-9 (4R,5R)-5-hydroxy-6-phenyl-4-hexanolide 
• 140844-93-5 3-((4R,5R)-5-Benzyl-2,2-dimethyl-[1,3]dioxolan-4-yl)-propionaldehyde 
• 151692-01-2 3-((4R,5R)-5-Benzyl-2,2-dimethyl-[1,3]dioxolan-4-yl)-propionic acid 

Relevant academic research and scientific papers

Synthesis of the (4R,5R)-Isomer of 5-Hydroxy-6-phenyl-4-hexanolide, a Lateral Root-inducing Substance Isolated from Erwinia quercina

Lipase-catalyzed enantioselective lactonization of racemic methyl 6-phenyl-4-hydroxy-5-hexynoate worked well to afford (R)-6-phenyl-5-hexyn-4-olide (42 percent yield, 81 percent e.e.).The e.e. of the product was enhanced to 97 percent by the repetition of